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Honokiol alleviates LPS-induced acute lung injury by inhibiting NLRP3 inflammasome-mediated pyroptosis via Nrf2 activation in vitro and in vivo

BACKGROUND: Honokiol (HKL) has been reported to ameliorate lipopolysaccharide (LPS)-induced acute lung injury (ALI). However, its potential mechanism of its protective effects remains unclear. In this study, the protective mechanism of HKL on LPS-induced ALI was explored in vivo and in vitro. METHOD...

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Detalles Bibliográficos
Autores principales:	Liu, Yuhan, Zhou, Jiabin, Luo, Yingying, Li, Jinxiao, Shang, Luorui, Zhou, Fangyuan, Yang, Shenglan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628413/ https://www.ncbi.nlm.nih.gov/pubmed/34844623 http://dx.doi.org/10.1186/s13020-021-00541-z

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