Expeditious recruitment of circulating memory CD8 T cells to the liver facilitates control of malaria

Circulating memory CD8 T cell trafficking and protective capacity during liver-stage malaria infection remains undefined. We find that effector memory CD8 T cells (Tem) infiltrate the liver within 6 hours after malarial or bacterial infections and mediate pathogen clearance. Tem recruitment coincide...

Descripción completa

Detalles Bibliográficos
Autores principales: Lefebvre, Mitchell N., Surette, Fionna A., Anthony, Scott M., Vijay, Rahul, Jensen, Isaac J., Pewe, Lecia L., Hancox, Lisa S., Van Braeckel-Budimir, Natalija, van de Wall, Stephanie, Urban, Stina L., Mix, Madison R., Kurup, Samarchith P., Badovinac, Vladimir P., Butler, Noah S., Harty, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628427/
https://www.ncbi.nlm.nih.gov/pubmed/34731605
http://dx.doi.org/10.1016/j.celrep.2021.109956

Ejemplares similares

Ejemplares similares