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Exploring the associations between transcript levels and fluxes in constraint-based models of metabolism

BACKGROUND: Several computational methods have been developed that integrate transcriptomics data with genome-scale metabolic reconstructions to increase accuracy of inferences of intracellular metabolic flux distributions. Even though existing methods use transcript abundances as a proxy for enzyme...

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Detalles Bibliográficos
Autores principales:	Sinha, Neeraj, van Schothorst, Evert M., Hooiveld, Guido J. E. J., Keijer, Jaap, Martins dos Santos, Vitor A. P., Suarez-Diez, Maria
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628452/ https://www.ncbi.nlm.nih.gov/pubmed/34839828 http://dx.doi.org/10.1186/s12859-021-04488-8

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