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Sensitivity to tumor development by TALEN-mediated Trp53 mutant genes in the susceptible FVB/N mice and the resistance C57BL/6 mice

BACKGROUND: This study was undertaken to compare the sensitivities of mice strains during tumor induction by transcription activator-like effector nucleases (TALEN)-mediated Trp53 mutant gene. Alterations of their tumorigenic phenotypes including survival rate, tumor formation and tumor spectrum, we...

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Detalles Bibliográficos
Autores principales:	Yun, Woo Bin, Kim, Ji Eun, Lee, Mi Lim, Choi, Jun Young, Park, Jin Ju, Song, Bo Ram, Kang, Byeong Cheol, Nam, Ki Taek, Lee, Han-Woong, Hwang, Dae Youn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628475/ https://www.ncbi.nlm.nih.gov/pubmed/34839833 http://dx.doi.org/10.1186/s42826-021-00107-y

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