Central Nervous System Effects of COVID-19 in People with HIV Infection

The convergence of the HIV and SARS-CoV-2 pandemics is an emerging field of interest. In this review, we outline the central nervous system (CNS) effects of COVID-19 in the general population and how these effects may manifest in people with HIV (PWH). We discuss the hypothetical mechanisms through...

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Autores principales: Peluso, Michael J., Hellmuth, Joanna, Chow, Felicia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Central Nervous System and Cognition (S Spudich, Section Editor)
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628487/
https://www.ncbi.nlm.nih.gov/pubmed/34843065
http://dx.doi.org/10.1007/s11904-021-00582-x
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author Peluso, Michael J.
Hellmuth, Joanna
Chow, Felicia C.
author_facet Peluso, Michael J.
Hellmuth, Joanna
Chow, Felicia C.
author_sort Peluso, Michael J.
collection PubMed
description The convergence of the HIV and SARS-CoV-2 pandemics is an emerging field of interest. In this review, we outline the central nervous system (CNS) effects of COVID-19 in the general population and how these effects may manifest in people with HIV (PWH). We discuss the hypothetical mechanisms through which SARS-CoV-2 could impact the CNS during both the acute and recovery phases of infection and the potential selective vulnerability of PWH to these effects as a result of epidemiologic, clinical, and biologic factors. Finally, we define key research questions and considerations for the investigation of CNS sequelae of COVID-19 in PWH.
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spelling pubmed-86284872021-11-29 Central Nervous System Effects of COVID-19 in People with HIV Infection Peluso, Michael J. Hellmuth, Joanna Chow, Felicia C. Curr HIV/AIDS Rep Central Nervous System and Cognition (S Spudich, Section Editor) The convergence of the HIV and SARS-CoV-2 pandemics is an emerging field of interest. In this review, we outline the central nervous system (CNS) effects of COVID-19 in the general population and how these effects may manifest in people with HIV (PWH). We discuss the hypothetical mechanisms through which SARS-CoV-2 could impact the CNS during both the acute and recovery phases of infection and the potential selective vulnerability of PWH to these effects as a result of epidemiologic, clinical, and biologic factors. Finally, we define key research questions and considerations for the investigation of CNS sequelae of COVID-19 in PWH. Springer US 2021-11-29 2021 /pmc/articles/PMC8628487/ /pubmed/34843065 http://dx.doi.org/10.1007/s11904-021-00582-x Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Central Nervous System and Cognition (S Spudich, Section Editor)
Peluso, Michael J.
Hellmuth, Joanna
Chow, Felicia C.
Central Nervous System Effects of COVID-19 in People with HIV Infection
title Central Nervous System Effects of COVID-19 in People with HIV Infection
title_full Central Nervous System Effects of COVID-19 in People with HIV Infection
title_fullStr Central Nervous System Effects of COVID-19 in People with HIV Infection
title_full_unstemmed Central Nervous System Effects of COVID-19 in People with HIV Infection
title_short Central Nervous System Effects of COVID-19 in People with HIV Infection
title_sort central nervous system effects of covid-19 in people with hiv infection
topic Central Nervous System and Cognition (S Spudich, Section Editor)
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628487/
https://www.ncbi.nlm.nih.gov/pubmed/34843065
http://dx.doi.org/10.1007/s11904-021-00582-x
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