Early manifestations and differential gene expression associated with photoreceptor degeneration in Prom1-deficient retina

Retinitis pigmentosa (RP) and macular dystrophy (MD) are characterized by gradual photoreceptor death in the retina and are often associated with genetic mutations, including those in the prominin-1 (Prom1) gene. Prom1-knockout (KO) mice recapitulate key features of these diseases including light-de...

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Detalles Bibliográficos
Autores principales: Kobayashi, Yuka, Watanabe, Shizuka, Ong, Agnes Lee Chen, Shirai, Manabu, Yamashiro, Chiemi, Ogata, Tadahiko, Higashijima, Fumiaki, Yoshimoto, Takuya, Hayano, Takahide, Asai, Yoshiyuki, Sasai, Noriaki, Kimura, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628633/
https://www.ncbi.nlm.nih.gov/pubmed/34664634
http://dx.doi.org/10.1242/dmm.048962

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