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BRCA1/2 Mutation Types Do Not Affect Prognosis in Ovarian Cancer Patients
Background: High grade serous ovarian carcinoma (HGSOC) is the most lethal type of epithelial ovarian cancer, with a prevalence of germline BRCA1/2 mutations as high as 20%. Our objective is to determine whether the location of mutations in the different domains of the BRCA1/2 genes affects the clin...
Autores principales: | Liontos, Michalis, Zografos, Eleni, Zoumpourlis, Panagiotis, Andrikopoulou, Angeliki, Svarna, Anna, Fiste, Oraianthi, Kunadis, Elena, Papatheodoridi, Alkistis Maria, Kaparelou, Maria, Koutsoukos, Konstantinos, Thomakos, Nikoloas, Haidopoulos, Dimitrios, Rodolakis, Alexandros, Dimopoulos, Meletios-Athanasios, Zagouri, Flora |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628789/ https://www.ncbi.nlm.nih.gov/pubmed/34898566 http://dx.doi.org/10.3390/curroncol28060377 |
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