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Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2

Introduction: The objective of this study was to evaluate the clinical and laboratory outcomes of solid cancer patients who were reinfected with COVID-19. Methods: Patients who were tested negative on the Coronavirus disease 2019 (COVID-19) PCR test and those with improved clinical conditions after...

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Autores principales: Ünsal, Oktay, Yazıcı, Ozan, Özdemir, Nuriye, Çubukçu, Erdem, Ocak, Birol, Üner, Aytuğ, Özet, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628862/
https://www.ncbi.nlm.nih.gov/pubmed/34825831
http://dx.doi.org/10.2217/fon-2021-0621
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author Ünsal, Oktay
Yazıcı, Ozan
Özdemir, Nuriye
Çubukçu, Erdem
Ocak, Birol
Üner, Aytuğ
Özet, Ahmet
author_facet Ünsal, Oktay
Yazıcı, Ozan
Özdemir, Nuriye
Çubukçu, Erdem
Ocak, Birol
Üner, Aytuğ
Özet, Ahmet
author_sort Ünsal, Oktay
collection PubMed
description Introduction: The objective of this study was to evaluate the clinical and laboratory outcomes of solid cancer patients who were reinfected with COVID-19. Methods: Patients who were tested negative on the Coronavirus disease 2019 (COVID-19) PCR test and those with improved clinical conditions after infection with COVID-19 were enrolled in this study. Patients who received a positive COVID-19 PCR test 28 days after the initial positive PCR test were considered as reinfected. Results: A total of 1024 patients with the diagnosis of solid malignancy and COVID-19 PCR positivity were examined. The reinfection rate was 3.1%. Mortality rate of reinfection was 34.3%. The serum ferritin and creatinine values in reinfection were found to be significantly higher than the first infection (respectively; p = 0.015, p = 0.014). Conclusion: This study has demonstrated one of the first preliminary clinical results of COVID-19 reinfection in solid cancer patients.
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spelling pubmed-86288622021-11-30 Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 Ünsal, Oktay Yazıcı, Ozan Özdemir, Nuriye Çubukçu, Erdem Ocak, Birol Üner, Aytuğ Özet, Ahmet Future Oncol Research Article Introduction: The objective of this study was to evaluate the clinical and laboratory outcomes of solid cancer patients who were reinfected with COVID-19. Methods: Patients who were tested negative on the Coronavirus disease 2019 (COVID-19) PCR test and those with improved clinical conditions after infection with COVID-19 were enrolled in this study. Patients who received a positive COVID-19 PCR test 28 days after the initial positive PCR test were considered as reinfected. Results: A total of 1024 patients with the diagnosis of solid malignancy and COVID-19 PCR positivity were examined. The reinfection rate was 3.1%. Mortality rate of reinfection was 34.3%. The serum ferritin and creatinine values in reinfection were found to be significantly higher than the first infection (respectively; p = 0.015, p = 0.014). Conclusion: This study has demonstrated one of the first preliminary clinical results of COVID-19 reinfection in solid cancer patients. Future Medicine Ltd 2021-11-26 2021-10 /pmc/articles/PMC8628862/ /pubmed/34825831 http://dx.doi.org/10.2217/fon-2021-0621 Text en © 2021 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Ünsal, Oktay
Yazıcı, Ozan
Özdemir, Nuriye
Çubukçu, Erdem
Ocak, Birol
Üner, Aytuğ
Özet, Ahmet
Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2
title Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2
title_full Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2
title_fullStr Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2
title_full_unstemmed Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2
title_short Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2
title_sort clinical and laboratory outcomes of the solid cancer patients reinfected with sars-cov-2
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628862/
https://www.ncbi.nlm.nih.gov/pubmed/34825831
http://dx.doi.org/10.2217/fon-2021-0621
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