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Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2
Introduction: The objective of this study was to evaluate the clinical and laboratory outcomes of solid cancer patients who were reinfected with COVID-19. Methods: Patients who were tested negative on the Coronavirus disease 2019 (COVID-19) PCR test and those with improved clinical conditions after...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628862/ https://www.ncbi.nlm.nih.gov/pubmed/34825831 http://dx.doi.org/10.2217/fon-2021-0621 |
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author | Ünsal, Oktay Yazıcı, Ozan Özdemir, Nuriye Çubukçu, Erdem Ocak, Birol Üner, Aytuğ Özet, Ahmet |
author_facet | Ünsal, Oktay Yazıcı, Ozan Özdemir, Nuriye Çubukçu, Erdem Ocak, Birol Üner, Aytuğ Özet, Ahmet |
author_sort | Ünsal, Oktay |
collection | PubMed |
description | Introduction: The objective of this study was to evaluate the clinical and laboratory outcomes of solid cancer patients who were reinfected with COVID-19. Methods: Patients who were tested negative on the Coronavirus disease 2019 (COVID-19) PCR test and those with improved clinical conditions after infection with COVID-19 were enrolled in this study. Patients who received a positive COVID-19 PCR test 28 days after the initial positive PCR test were considered as reinfected. Results: A total of 1024 patients with the diagnosis of solid malignancy and COVID-19 PCR positivity were examined. The reinfection rate was 3.1%. Mortality rate of reinfection was 34.3%. The serum ferritin and creatinine values in reinfection were found to be significantly higher than the first infection (respectively; p = 0.015, p = 0.014). Conclusion: This study has demonstrated one of the first preliminary clinical results of COVID-19 reinfection in solid cancer patients. |
format | Online Article Text |
id | pubmed-8628862 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Future Medicine Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-86288622021-11-30 Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 Ünsal, Oktay Yazıcı, Ozan Özdemir, Nuriye Çubukçu, Erdem Ocak, Birol Üner, Aytuğ Özet, Ahmet Future Oncol Research Article Introduction: The objective of this study was to evaluate the clinical and laboratory outcomes of solid cancer patients who were reinfected with COVID-19. Methods: Patients who were tested negative on the Coronavirus disease 2019 (COVID-19) PCR test and those with improved clinical conditions after infection with COVID-19 were enrolled in this study. Patients who received a positive COVID-19 PCR test 28 days after the initial positive PCR test were considered as reinfected. Results: A total of 1024 patients with the diagnosis of solid malignancy and COVID-19 PCR positivity were examined. The reinfection rate was 3.1%. Mortality rate of reinfection was 34.3%. The serum ferritin and creatinine values in reinfection were found to be significantly higher than the first infection (respectively; p = 0.015, p = 0.014). Conclusion: This study has demonstrated one of the first preliminary clinical results of COVID-19 reinfection in solid cancer patients. Future Medicine Ltd 2021-11-26 2021-10 /pmc/articles/PMC8628862/ /pubmed/34825831 http://dx.doi.org/10.2217/fon-2021-0621 Text en © 2021 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) |
spellingShingle | Research Article Ünsal, Oktay Yazıcı, Ozan Özdemir, Nuriye Çubukçu, Erdem Ocak, Birol Üner, Aytuğ Özet, Ahmet Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 |
title | Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 |
title_full | Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 |
title_fullStr | Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 |
title_full_unstemmed | Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 |
title_short | Clinical and laboratory outcomes of the solid cancer patients reinfected with SARS-CoV-2 |
title_sort | clinical and laboratory outcomes of the solid cancer patients reinfected with sars-cov-2 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628862/ https://www.ncbi.nlm.nih.gov/pubmed/34825831 http://dx.doi.org/10.2217/fon-2021-0621 |
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