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Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature

Background and Purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China in December 2019. Symptoms range from mild flu-like symptoms to more severe presentations, including pneumonia, acute respiratory distress syndrome (ARDS), and even death...

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Autores principales: Sriwastava, Shitiz, Shrestha, Ashish K., Khalid, Syed Hassan, Colantonio, Mark A., Nwafor, Divine, Srivastava, Samiksha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628885/
https://www.ncbi.nlm.nih.gov/pubmed/34842783
http://dx.doi.org/10.3390/neurolint13040061
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author Sriwastava, Shitiz
Shrestha, Ashish K.
Khalid, Syed Hassan
Colantonio, Mark A.
Nwafor, Divine
Srivastava, Samiksha
author_facet Sriwastava, Shitiz
Shrestha, Ashish K.
Khalid, Syed Hassan
Colantonio, Mark A.
Nwafor, Divine
Srivastava, Samiksha
author_sort Sriwastava, Shitiz
collection PubMed
description Background and Purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China in December 2019. Symptoms range from mild flu-like symptoms to more severe presentations, including pneumonia, acute respiratory distress syndrome (ARDS), and even death. In response to the COVID-19 pandemic, the Emergency Use Authorization (EUA) approved the use of several vaccines. Because vaccines have been fast-tracked for emergency use, the short and long-term safety profile has been an area of concern. The aim of this paper is to extensively review published literature regarding post-COVID-19 vaccination neurological complications and characterize neuroimaging findings from three case presentations for early diagnosis and treatment. Methods: The analysis includes data from PubMed and Google Scholar. Articles included were retrieved from database inception beginning December 2020 with no language restrictions. Terms used include “SARS-CoV-2”, “post Covid vaccination”, “neurological complications”, “Guillain-barre Syndrome”, “Transverse-myelitis”, “Cerebral Venous Sinus thrombosis”, and “Cerebral hemorrhage”. Results: The literature review yielded several neurological complications post vaccination, including cerebral sinus venous thrombosis, transverse myelitis, Guillain-Barré Syndrome and optic neuritis, to name a few. Patient case presentation findings were consistent with documented results in published literature. Conclusions: We present a case series with a thorough literature review documenting adverse neurological affects following COVID-19 vaccination. Our case presentations and literature review highlight the importance of neuroimaging when diagnosing post-COVID-19 vaccination adverse effects. MRI imaging study is an important tool to be considered in patients presenting with post-COVID-19 vaccination-related unexplained neurological symptoms for accurate diagnosis.
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spelling pubmed-86288852021-11-30 Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature Sriwastava, Shitiz Shrestha, Ashish K. Khalid, Syed Hassan Colantonio, Mark A. Nwafor, Divine Srivastava, Samiksha Neurol Int Review Background and Purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China in December 2019. Symptoms range from mild flu-like symptoms to more severe presentations, including pneumonia, acute respiratory distress syndrome (ARDS), and even death. In response to the COVID-19 pandemic, the Emergency Use Authorization (EUA) approved the use of several vaccines. Because vaccines have been fast-tracked for emergency use, the short and long-term safety profile has been an area of concern. The aim of this paper is to extensively review published literature regarding post-COVID-19 vaccination neurological complications and characterize neuroimaging findings from three case presentations for early diagnosis and treatment. Methods: The analysis includes data from PubMed and Google Scholar. Articles included were retrieved from database inception beginning December 2020 with no language restrictions. Terms used include “SARS-CoV-2”, “post Covid vaccination”, “neurological complications”, “Guillain-barre Syndrome”, “Transverse-myelitis”, “Cerebral Venous Sinus thrombosis”, and “Cerebral hemorrhage”. Results: The literature review yielded several neurological complications post vaccination, including cerebral sinus venous thrombosis, transverse myelitis, Guillain-Barré Syndrome and optic neuritis, to name a few. Patient case presentation findings were consistent with documented results in published literature. Conclusions: We present a case series with a thorough literature review documenting adverse neurological affects following COVID-19 vaccination. Our case presentations and literature review highlight the importance of neuroimaging when diagnosing post-COVID-19 vaccination adverse effects. MRI imaging study is an important tool to be considered in patients presenting with post-COVID-19 vaccination-related unexplained neurological symptoms for accurate diagnosis. MDPI 2021-11-19 /pmc/articles/PMC8628885/ /pubmed/34842783 http://dx.doi.org/10.3390/neurolint13040061 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Sriwastava, Shitiz
Shrestha, Ashish K.
Khalid, Syed Hassan
Colantonio, Mark A.
Nwafor, Divine
Srivastava, Samiksha
Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature
title Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature
title_full Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature
title_fullStr Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature
title_full_unstemmed Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature
title_short Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature
title_sort spectrum of neuroimaging findings in post-covid-19 vaccination: a case series and review of literature
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628885/
https://www.ncbi.nlm.nih.gov/pubmed/34842783
http://dx.doi.org/10.3390/neurolint13040061
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