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Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature
Background and Purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China in December 2019. Symptoms range from mild flu-like symptoms to more severe presentations, including pneumonia, acute respiratory distress syndrome (ARDS), and even death...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628885/ https://www.ncbi.nlm.nih.gov/pubmed/34842783 http://dx.doi.org/10.3390/neurolint13040061 |
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author | Sriwastava, Shitiz Shrestha, Ashish K. Khalid, Syed Hassan Colantonio, Mark A. Nwafor, Divine Srivastava, Samiksha |
author_facet | Sriwastava, Shitiz Shrestha, Ashish K. Khalid, Syed Hassan Colantonio, Mark A. Nwafor, Divine Srivastava, Samiksha |
author_sort | Sriwastava, Shitiz |
collection | PubMed |
description | Background and Purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China in December 2019. Symptoms range from mild flu-like symptoms to more severe presentations, including pneumonia, acute respiratory distress syndrome (ARDS), and even death. In response to the COVID-19 pandemic, the Emergency Use Authorization (EUA) approved the use of several vaccines. Because vaccines have been fast-tracked for emergency use, the short and long-term safety profile has been an area of concern. The aim of this paper is to extensively review published literature regarding post-COVID-19 vaccination neurological complications and characterize neuroimaging findings from three case presentations for early diagnosis and treatment. Methods: The analysis includes data from PubMed and Google Scholar. Articles included were retrieved from database inception beginning December 2020 with no language restrictions. Terms used include “SARS-CoV-2”, “post Covid vaccination”, “neurological complications”, “Guillain-barre Syndrome”, “Transverse-myelitis”, “Cerebral Venous Sinus thrombosis”, and “Cerebral hemorrhage”. Results: The literature review yielded several neurological complications post vaccination, including cerebral sinus venous thrombosis, transverse myelitis, Guillain-Barré Syndrome and optic neuritis, to name a few. Patient case presentation findings were consistent with documented results in published literature. Conclusions: We present a case series with a thorough literature review documenting adverse neurological affects following COVID-19 vaccination. Our case presentations and literature review highlight the importance of neuroimaging when diagnosing post-COVID-19 vaccination adverse effects. MRI imaging study is an important tool to be considered in patients presenting with post-COVID-19 vaccination-related unexplained neurological symptoms for accurate diagnosis. |
format | Online Article Text |
id | pubmed-8628885 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86288852021-11-30 Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature Sriwastava, Shitiz Shrestha, Ashish K. Khalid, Syed Hassan Colantonio, Mark A. Nwafor, Divine Srivastava, Samiksha Neurol Int Review Background and Purpose: The novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China in December 2019. Symptoms range from mild flu-like symptoms to more severe presentations, including pneumonia, acute respiratory distress syndrome (ARDS), and even death. In response to the COVID-19 pandemic, the Emergency Use Authorization (EUA) approved the use of several vaccines. Because vaccines have been fast-tracked for emergency use, the short and long-term safety profile has been an area of concern. The aim of this paper is to extensively review published literature regarding post-COVID-19 vaccination neurological complications and characterize neuroimaging findings from three case presentations for early diagnosis and treatment. Methods: The analysis includes data from PubMed and Google Scholar. Articles included were retrieved from database inception beginning December 2020 with no language restrictions. Terms used include “SARS-CoV-2”, “post Covid vaccination”, “neurological complications”, “Guillain-barre Syndrome”, “Transverse-myelitis”, “Cerebral Venous Sinus thrombosis”, and “Cerebral hemorrhage”. Results: The literature review yielded several neurological complications post vaccination, including cerebral sinus venous thrombosis, transverse myelitis, Guillain-Barré Syndrome and optic neuritis, to name a few. Patient case presentation findings were consistent with documented results in published literature. Conclusions: We present a case series with a thorough literature review documenting adverse neurological affects following COVID-19 vaccination. Our case presentations and literature review highlight the importance of neuroimaging when diagnosing post-COVID-19 vaccination adverse effects. MRI imaging study is an important tool to be considered in patients presenting with post-COVID-19 vaccination-related unexplained neurological symptoms for accurate diagnosis. MDPI 2021-11-19 /pmc/articles/PMC8628885/ /pubmed/34842783 http://dx.doi.org/10.3390/neurolint13040061 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Sriwastava, Shitiz Shrestha, Ashish K. Khalid, Syed Hassan Colantonio, Mark A. Nwafor, Divine Srivastava, Samiksha Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature |
title | Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature |
title_full | Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature |
title_fullStr | Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature |
title_full_unstemmed | Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature |
title_short | Spectrum of Neuroimaging Findings in Post-COVID-19 Vaccination: A Case Series and Review of Literature |
title_sort | spectrum of neuroimaging findings in post-covid-19 vaccination: a case series and review of literature |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628885/ https://www.ncbi.nlm.nih.gov/pubmed/34842783 http://dx.doi.org/10.3390/neurolint13040061 |
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