Cargando…

Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures

Improvements in software for image analysis have enabled advances in both medical and engineering industries, including the use of medical analysis tools to recreate internal parts of the human body accurately. A research analysis found that FDM-sourced elements have shown viability for a customized...

Descripción completa

Detalles Bibliográficos
Autores principales: Frizziero, Leonardo, Santi, Gian Maria, Leon-Cardenas, Christian, Ferretti, Patrich, Sali, Merve, Gianese, Francesco, Crescentini, Nicola, Donnici, Giampiero, Liverani, Alfredo, Trisolino, Giovanni, Zarantonello, Paola, Stallone, Stefano, Di Gennaro, Giovanni Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628910/
https://www.ncbi.nlm.nih.gov/pubmed/34842761
http://dx.doi.org/10.3390/jfb12040063
_version_ 1784607094699196416
author Frizziero, Leonardo
Santi, Gian Maria
Leon-Cardenas, Christian
Ferretti, Patrich
Sali, Merve
Gianese, Francesco
Crescentini, Nicola
Donnici, Giampiero
Liverani, Alfredo
Trisolino, Giovanni
Zarantonello, Paola
Stallone, Stefano
Di Gennaro, Giovanni Luigi
author_facet Frizziero, Leonardo
Santi, Gian Maria
Leon-Cardenas, Christian
Ferretti, Patrich
Sali, Merve
Gianese, Francesco
Crescentini, Nicola
Donnici, Giampiero
Liverani, Alfredo
Trisolino, Giovanni
Zarantonello, Paola
Stallone, Stefano
Di Gennaro, Giovanni Luigi
author_sort Frizziero, Leonardo
collection PubMed
description Improvements in software for image analysis have enabled advances in both medical and engineering industries, including the use of medical analysis tools to recreate internal parts of the human body accurately. A research analysis found that FDM-sourced elements have shown viability for a customized and reliable approach in the orthopedics field. Three-dimensional printing has allowed enhanced accuracy of preoperative planning, leading to reduced surgery times, fewer unnecessary tissue perforations, and fewer healing complications. Furthermore, using custom tools chosen for each procedure has shown the best results. Bone correction-related surgeries require customized cutting guides for a greater outcome. This study aims to assess the biopolymer-based tools for surgical operations and their ability to sustain a regular heat-sterilization cycle without compromising the geometry and fit characteristics for a proper procedure. To achieve this, a DICOM and FDM methodology is proposed for fast prototyping of the cutting guide by means of 3D engineering. A sterilization test was performed on HTPLA, PLA, and nylon polymers. As a result, the unique characteristics within the regular autoclave sterilization process allowed regular supplied PLA to show there were no significant deformations, whilst annealed HTPLA proved this material’s capability of sustaining repeated heat cycles due to its crystallization properties. Both of these proved that the sterilization procedures do not compromise the reliability of the part, nor the safety of the procedure. Therefore, prototypes made with a similar process as this proposal could be safely used in actual surgery practices, while nylon performed poorly because of its hygroscopic properties.
format Online
Article
Text
id pubmed-8628910
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-86289102021-11-30 Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures Frizziero, Leonardo Santi, Gian Maria Leon-Cardenas, Christian Ferretti, Patrich Sali, Merve Gianese, Francesco Crescentini, Nicola Donnici, Giampiero Liverani, Alfredo Trisolino, Giovanni Zarantonello, Paola Stallone, Stefano Di Gennaro, Giovanni Luigi J Funct Biomater Article Improvements in software for image analysis have enabled advances in both medical and engineering industries, including the use of medical analysis tools to recreate internal parts of the human body accurately. A research analysis found that FDM-sourced elements have shown viability for a customized and reliable approach in the orthopedics field. Three-dimensional printing has allowed enhanced accuracy of preoperative planning, leading to reduced surgery times, fewer unnecessary tissue perforations, and fewer healing complications. Furthermore, using custom tools chosen for each procedure has shown the best results. Bone correction-related surgeries require customized cutting guides for a greater outcome. This study aims to assess the biopolymer-based tools for surgical operations and their ability to sustain a regular heat-sterilization cycle without compromising the geometry and fit characteristics for a proper procedure. To achieve this, a DICOM and FDM methodology is proposed for fast prototyping of the cutting guide by means of 3D engineering. A sterilization test was performed on HTPLA, PLA, and nylon polymers. As a result, the unique characteristics within the regular autoclave sterilization process allowed regular supplied PLA to show there were no significant deformations, whilst annealed HTPLA proved this material’s capability of sustaining repeated heat cycles due to its crystallization properties. Both of these proved that the sterilization procedures do not compromise the reliability of the part, nor the safety of the procedure. Therefore, prototypes made with a similar process as this proposal could be safely used in actual surgery practices, while nylon performed poorly because of its hygroscopic properties. MDPI 2021-11-19 /pmc/articles/PMC8628910/ /pubmed/34842761 http://dx.doi.org/10.3390/jfb12040063 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Frizziero, Leonardo
Santi, Gian Maria
Leon-Cardenas, Christian
Ferretti, Patrich
Sali, Merve
Gianese, Francesco
Crescentini, Nicola
Donnici, Giampiero
Liverani, Alfredo
Trisolino, Giovanni
Zarantonello, Paola
Stallone, Stefano
Di Gennaro, Giovanni Luigi
Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures
title Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures
title_full Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures
title_fullStr Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures
title_full_unstemmed Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures
title_short Heat Sterilization Effects on Polymeric, FDM-Optimized Orthopedic Cutting Guide for Surgical Procedures
title_sort heat sterilization effects on polymeric, fdm-optimized orthopedic cutting guide for surgical procedures
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8628910/
https://www.ncbi.nlm.nih.gov/pubmed/34842761
http://dx.doi.org/10.3390/jfb12040063
work_keys_str_mv AT frizzieroleonardo heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT santigianmaria heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT leoncardenaschristian heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT ferrettipatrich heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT salimerve heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT gianesefrancesco heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT crescentininicola heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT donnicigiampiero heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT liveranialfredo heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT trisolinogiovanni heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT zarantonellopaola heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT stallonestefano heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures
AT digennarogiovanniluigi heatsterilizationeffectsonpolymericfdmoptimizedorthopediccuttingguideforsurgicalprocedures