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Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report
Zolpidem is an imidazopyridine derivative and a non-benzodiazepine hypnotic drug. There are several case reports of zolpidem abuse or dependence and zolpidem withdrawal. This study reports a case of paroxysmal tonic spasm (PTS) after abrupt withdrawal of high dose zolpidem. The case was a 21-year- o...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Giovanni Fioriti Editore srl
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629039/ https://www.ncbi.nlm.nih.gov/pubmed/34909009 http://dx.doi.org/10.36131/cnfioritieditore20200507 |
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author | Keighobadi, Masoud Karimi, Narges |
author_facet | Keighobadi, Masoud Karimi, Narges |
author_sort | Keighobadi, Masoud |
collection | PubMed |
description | Zolpidem is an imidazopyridine derivative and a non-benzodiazepine hypnotic drug. There are several case reports of zolpidem abuse or dependence and zolpidem withdrawal. This study reports a case of paroxysmal tonic spasm (PTS) after abrupt withdrawal of high dose zolpidem. The case was a 21-year- old male patient with complaints of acute involuntary and painful spasms of all extremities after the sudden withdrawal of taking supratherapeutic zolpidem. In his medical records, He had the history of insomnia and psychiatric disorder . The patientʼs symptoms improved with intravenous injection of 10 mg diazepam slowly and zolpidem was tapered gradually. This case report indicates that zolpidem has a dependency and abusage properties. To the best of our knowledge , this is the first report of zolpidem withdrawal with PTS. |
format | Online Article Text |
id | pubmed-8629039 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Giovanni Fioriti Editore srl |
record_format | MEDLINE/PubMed |
spelling | pubmed-86290392021-12-13 Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report Keighobadi, Masoud Karimi, Narges Clin Neuropsychiatry Case Report Zolpidem is an imidazopyridine derivative and a non-benzodiazepine hypnotic drug. There are several case reports of zolpidem abuse or dependence and zolpidem withdrawal. This study reports a case of paroxysmal tonic spasm (PTS) after abrupt withdrawal of high dose zolpidem. The case was a 21-year- old male patient with complaints of acute involuntary and painful spasms of all extremities after the sudden withdrawal of taking supratherapeutic zolpidem. In his medical records, He had the history of insomnia and psychiatric disorder . The patientʼs symptoms improved with intravenous injection of 10 mg diazepam slowly and zolpidem was tapered gradually. This case report indicates that zolpidem has a dependency and abusage properties. To the best of our knowledge , this is the first report of zolpidem withdrawal with PTS. Giovanni Fioriti Editore srl 2020-10 /pmc/articles/PMC8629039/ /pubmed/34909009 http://dx.doi.org/10.36131/cnfioritieditore20200507 Text en © 2020 Giovanni Fioriti Editore s.r.l. This is an open access article. Distribution and reproduction are permitted in any medium, provided the original author(s) and source are credited. |
spellingShingle | Case Report Keighobadi, Masoud Karimi, Narges Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report |
title | Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report |
title_full | Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report |
title_fullStr | Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report |
title_full_unstemmed | Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report |
title_short | Paroxysmal Tonic Spasm in a Patient with the Sudden Zolpidem Withdrawal: A Case Report |
title_sort | paroxysmal tonic spasm in a patient with the sudden zolpidem withdrawal: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629039/ https://www.ncbi.nlm.nih.gov/pubmed/34909009 http://dx.doi.org/10.36131/cnfioritieditore20200507 |
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