Peripheral airways type 2 inflammation, neutrophilia and microbial dysbiosis in severe asthma

BACKGROUND: IL‐13 is considered an archetypal T2 cytokine central to the clinical disease expression of asthma. The IL‐13 response genes, which are upregulated in central airway bronchial epithelial of asthma patients, can be normalized by high‐dose inhaled steroid therapy in severe asthma. However,...

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Detalles Bibliográficos
Autores principales: Azim, Adnan, Green, Ben, Lau, Laurie, Rupani, Hitasha, Jayasekera, Nivenka, Bruce, Kenneth, Howarth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
ORIGINAL ARTICLES
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629111/
https://www.ncbi.nlm.nih.gov/pubmed/33411348
http://dx.doi.org/10.1111/all.14732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629111/
https://www.ncbi.nlm.nih.gov/pubmed/33411348
http://dx.doi.org/10.1111/all.14732

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