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Peripheral airways type 2 inflammation, neutrophilia and microbial dysbiosis in severe asthma
BACKGROUND: IL‐13 is considered an archetypal T2 cytokine central to the clinical disease expression of asthma. The IL‐13 response genes, which are upregulated in central airway bronchial epithelial of asthma patients, can be normalized by high‐dose inhaled steroid therapy in severe asthma. However,...
Autores principales: | Azim, Adnan, Green, Ben, Lau, Laurie, Rupani, Hitasha, Jayasekera, Nivenka, Bruce, Kenneth, Howarth, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629111/ https://www.ncbi.nlm.nih.gov/pubmed/33411348 http://dx.doi.org/10.1111/all.14732 |
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