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Systematic temporal analysis of peripheral blood transcriptomes using TrendCatcher identifies early and persistent neutrophil activation as a hallmark of severe COVID-19

Studying temporal gene expression shifts during disease progression provides important insights into the biological mechanisms that distinguish adaptive and maladaptive responses. Existing tools for the analysis of time course transcriptomic data are not designed to optimally identify distinct tempo...

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Detalles Bibliográficos
Autores principales: Wang, Xinge, Sanborn, Mark, Dai, Yang, Rehman, Jalees
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629189/
https://www.ncbi.nlm.nih.gov/pubmed/34845446
http://dx.doi.org/10.1101/2021.05.04.442617

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