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Systematic temporal analysis of peripheral blood transcriptomes using TrendCatcher identifies early and persistent neutrophil activation as a hallmark of severe COVID-19
Studying temporal gene expression shifts during disease progression provides important insights into the biological mechanisms that distinguish adaptive and maladaptive responses. Existing tools for the analysis of time course transcriptomic data are not designed to optimally identify distinct tempo...
Autores principales: | Wang, Xinge, Sanborn, Mark, Dai, Yang, Rehman, Jalees |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629189/ https://www.ncbi.nlm.nih.gov/pubmed/34845446 http://dx.doi.org/10.1101/2021.05.04.442617 |
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