Severe COVID-19 infection is associated with aberrant cytokine production by infected lung epithelial cells rather than by systemic immune dysfunction

The mechanisms explaining progression to severe COVID-19 remain poorly understood. It has been proposed that immune system dysregulation/over-stimulation may be implicated, but it is not clear how such processes would lead to respiratory failure. We performed comprehensive multiparameter immune moni...

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Detalles Bibliográficos
Autores principales: Rouhani, Sherin J, Trujillo, Jonathan A, Pyzer, Athalia R, Yu, Jovian, Fessler, Jessica, Cabanov, Alexandra, Higgs, Emily F, Cron, Kyle R., Zha, Yuanyuan, Lu, Yihao, Bloodworth, Jeffrey C., Abasiyanik, Mustafa Fatih, Okrah, Susan, Flood, Blake A, Hatogai, Ken, Leung, Michael YK, Pezeshk, Apameh, Kozloff, Lara, Reschke, Robin, Strohbehn, Garth W., Chervin, Carolina Soto, Kumar, Madan, Schrantz, Stephen, Madariaga, Maria Lucia, Beavis, Kathleen G, Yeo, Kiang-Teck J., Sweis, Randy F., Segal, Jeremy, Tay, Savaş, Izumchenko, Evgeny, Mueller, Jeffrey, Chen, Lin S, Gajewski, Thomas F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629200/
https://www.ncbi.nlm.nih.gov/pubmed/34845442
http://dx.doi.org/10.21203/rs.3.rs-1083825/v1

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