A large-scale transgenic RNAi screen identifies transcription factors that modulate myofiber size in Drosophila

Myofiber atrophy occurs with aging and in many diseases but the underlying mechanisms are incompletely understood. Here, we have used >1,100 muscle-targeted RNAi interventions to comprehensively assess the function of 447 transcription factors in the developmental growth of body wall skeletal mus...

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Detalles Bibliográficos
Autores principales: Graca, Flavia A., Sheffield, Natalie, Puppa, Melissa, Finkelstein, David, Hunt, Liam C., Demontis, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629395/
https://www.ncbi.nlm.nih.gov/pubmed/34780463
http://dx.doi.org/10.1371/journal.pgen.1009926

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629395/
https://www.ncbi.nlm.nih.gov/pubmed/34780463
http://dx.doi.org/10.1371/journal.pgen.1009926

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