Anticancer Effect of Rh2, a Histone Deacetylase Inhibitor, in HepG2 Cells and HepG2 Cell-Derived Xenograft Tumors Occurs via the Inhibition of HDACs and Activation of the MAPK Signaling Pathway

PURPOSE: To investigate the effect of 20(S)-ginsenoside Rh2 (Rh2) on anti HepG2 liver cancer cells and HepG2 cell-derived xenograft tumors, and explore the underlying mechanisms. MATERIALS AND METHODS: The activity of total HDACs and HAT were assessed with a HDACs colorimetric kit. Expression of HDA...

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Detalles Bibliográficos
Autores principales: Qiang, Shi Qing, Qin, Gao Chao, Jing, Li, Qiang, Feng Zi, Mei, Qin Hong, Long, Chen Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629470/
https://www.ncbi.nlm.nih.gov/pubmed/34452568
http://dx.doi.org/10.31557/APJCP.2021.22.8.2529

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