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The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study
Optical coherence tomography angiography (OCTA) was used to analyze the alterations in the density of retinal blood vessels and the choriocapillaris (VD) in patients suffering from type 2 diabetes mellitus (T2DM). One hundred sixty-six eyes of 83 patients (43 of whom were men and 40 women, with a me...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629665/ https://www.ncbi.nlm.nih.gov/pubmed/34853704 http://dx.doi.org/10.1155/2021/7043251 |
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author | Zlatanović, Marko Đorđević Jocić, Jasmina Jakšić, Vesna Zlatanović, Nevena Golubović, Mlađan Živković, Maja |
author_facet | Zlatanović, Marko Đorđević Jocić, Jasmina Jakšić, Vesna Zlatanović, Nevena Golubović, Mlađan Živković, Maja |
author_sort | Zlatanović, Marko |
collection | PubMed |
description | Optical coherence tomography angiography (OCTA) was used to analyze the alterations in the density of retinal blood vessels and the choriocapillaris (VD) in patients suffering from type 2 diabetes mellitus (T2DM). One hundred sixty-six eyes of 83 patients (43 of whom were men and 40 women, with a mean age of 58.59 ± 14.04) with T2DM and without diabetic retinopathy were examined for the purpose of conducting the observational prospective study. The control group (CG) consisted of 66 eyes in 33 healthy subjects (15 male and 18 female, with a mean age of 55.12 ± 12.70). The measurement regions of vessel density (VD) included the deep capillary plexus (DCP), the superficial capillary plexus (SCP), and the choriocapillaris. The results indicate considerable differences in the VD of the DCP and SCP when comparing the control group with the study groups (p < 0.001). In comparison with the control group (p < 0.001), there was a statistically significant reduction in the VD of the choriocapillaris in the study group. Furthermore, patients with T2DM showed a significantly decreased VD concerning the control in different macular regions. Thickness in several macular regions in the study group significantly decreased compared to the ones in the control group. OCTA was used to gather relevant information about the vascular changes which occurred in T2DM patients, assessed through the quantitative analysis of the blood flow in the retina and choriocapillaris. |
format | Online Article Text |
id | pubmed-8629665 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-86296652021-11-30 The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study Zlatanović, Marko Đorđević Jocić, Jasmina Jakšić, Vesna Zlatanović, Nevena Golubović, Mlađan Živković, Maja J Ophthalmol Research Article Optical coherence tomography angiography (OCTA) was used to analyze the alterations in the density of retinal blood vessels and the choriocapillaris (VD) in patients suffering from type 2 diabetes mellitus (T2DM). One hundred sixty-six eyes of 83 patients (43 of whom were men and 40 women, with a mean age of 58.59 ± 14.04) with T2DM and without diabetic retinopathy were examined for the purpose of conducting the observational prospective study. The control group (CG) consisted of 66 eyes in 33 healthy subjects (15 male and 18 female, with a mean age of 55.12 ± 12.70). The measurement regions of vessel density (VD) included the deep capillary plexus (DCP), the superficial capillary plexus (SCP), and the choriocapillaris. The results indicate considerable differences in the VD of the DCP and SCP when comparing the control group with the study groups (p < 0.001). In comparison with the control group (p < 0.001), there was a statistically significant reduction in the VD of the choriocapillaris in the study group. Furthermore, patients with T2DM showed a significantly decreased VD concerning the control in different macular regions. Thickness in several macular regions in the study group significantly decreased compared to the ones in the control group. OCTA was used to gather relevant information about the vascular changes which occurred in T2DM patients, assessed through the quantitative analysis of the blood flow in the retina and choriocapillaris. Hindawi 2021-11-22 /pmc/articles/PMC8629665/ /pubmed/34853704 http://dx.doi.org/10.1155/2021/7043251 Text en Copyright © 2021 Marko Zlatanović et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Zlatanović, Marko Đorđević Jocić, Jasmina Jakšić, Vesna Zlatanović, Nevena Golubović, Mlađan Živković, Maja The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study |
title | The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study |
title_full | The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study |
title_fullStr | The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study |
title_full_unstemmed | The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study |
title_short | The Determination of Type 2 Diabetes Mellitus's Impact on the Density of Retinal Blood Vessels and the Choriocapillaris: Optical Coherence Tomography Angiography Study |
title_sort | determination of type 2 diabetes mellitus's impact on the density of retinal blood vessels and the choriocapillaris: optical coherence tomography angiography study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629665/ https://www.ncbi.nlm.nih.gov/pubmed/34853704 http://dx.doi.org/10.1155/2021/7043251 |
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