Cargando…

A Case of Acute Myeloid Leukemia Harboring a Rare Three-Way Translocation t(5;7;7) Involving the PDGFRB Gene and Successfully Treated with Imatinib

Platelet-derived growth factor-beta (PDGFRB) gene maps for the receptor tyrosine kinase PDGRFβ. PDGFRB gene fusions have been implicated in multiple myeloid and lymphoid neoplasms and have shown exquisite sensitivity to tyrosine kinase inhibitors. We report a case of a 29-year-old male who presented...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borogovac, Azra, Sahu, Kamal Kant, Vishwanathan, Ganesh Kumar, Miron, Patricia Minehart, Cerny, Jan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629764/ https://www.ncbi.nlm.nih.gov/pubmed/34858057 http://dx.doi.org/10.2147/CMAR.S324718

Ejemplares similares

Novel PDGFRB rearrangement in multifocal infantile myofibromatosis is tumorigenic and sensitive to imatinib
por: Hassan, Mohammed, et al.
Publicado: (2019)

Myeloid/Lymphoid Neoplasm with PDGFRB Rearrangement with t(5;10)(q33;q22) Harboring a Novel Breakpoint of the CCDC6-PDGFRB Fusion Gene
por: Yamazaki, Miki, et al.
Publicado: (2019)

OR7-002 – Pyrin 577 mutations in dominant autoinflammation
por: Stoffels, M, et al.
Publicado: (2013)

Myeloid Neoplasm with PCM1-PDGFRB Transcript Responded to Low-Dose Imatinib: One Case Report with Literature Review
por: Wang, Zhe, et al.
Publicado: (2022)

Effects of Sunitinib and Other Kinase Inhibitors on Cells Harboring a PDGFRB Mutation Associated with Infantile Myofibromatosis
por: Sramek, Martin, et al.
Publicado: (2018)

Genomic and clinical findings in myeloid neoplasms with PDGFRB rearrangement
por: Di Giacomo, Danika, et al.
Publicado: (2021)

Novel t(5;19) Translocation in a Patient with PDGFRB Associated Chronic Leukemia: Implications for Treatment Strategy
por: Provenzano, Joel D., et al.
Publicado: (2013)

The EBF1-PDGFRB T681I mutation is highly resistant to imatinib and dasatinib in vitro and detectable in clinical samples prior to treatment
por: Tran, Thai Hoa, et al.
Publicado: (2021)

A novel cytogenetic abnormality t(7;8)(p11.2:q11.2) and a four-way Philadelphia translocation in an imatinib mesylate-resistant chronic myeloid leukemia patient
por: AL-ACHKAR, WALID, et al.
Publicado: (2013)

Rare gene fusion rearrangement SPTNB1-PDGFRB in an atypical myeloproliferative neoplasm
por: Furtado, Vanessa Fiorini, et al.
Publicado: (2018)

Myeloid Neoplasms with t(5;12) and ETV6-ACSL6 Gene Fusion, Potential Mimickers of Myeloid Neoplasm with PDGFRB Rearrangement: Case Report with Imatinib Therapy and Review of the Literature
por: De Luca-Johnson, Javier, et al.
Publicado: (2016)

Recurrent PDGFRB mutations in unicentric Castleman disease
por: Li, Zhaoming, et al.
Publicado: (2019)

Case of cryptic TNIP1::PDGFRB rearrangement presenting with myelodysplastic syndrome achieved hematologic and cytogenetic remission with low-dose imatinib plus decitabine therapy
por: Qu, Shiqiang, et al.
Publicado: (2023)

Evidence for PDGFRA, PDGFRB and KIT deregulation in an NSCLC patient
por: Negri, T, et al.
Publicado: (2007)

Corneal Vascularization Associated With a Novel PDGFRB Variant
por: Gladkauskas, Titas, et al.
Publicado: (2023)

SAT-577 Severe Asymptomatic Hypertriglyceridemia
por: Rodriguez, Daniel, et al.
Publicado: (2020)

6-Amino-8-(2-bromophenyl)-1,7,8,8a-tetrahydro-3H-isothiochromene-5,7,7-tricarbonitrile dimethylformamide solvate
por: Zhang, Hai-Yan, et al.
Publicado: (2009)

Inhibition of the platelet-derived growth factor receptor beta (PDGFRB) using gene silencing, crenolanib besylate, or imatinib mesylate hampers the malignant phenotype of mesothelioma cell lines
por: Melaiu, Ombretta, et al.
Publicado: (2017)

Concurrent acute myeloid leukemia and T lymphoblastic lymphoma in a patient with rearranged PDGFRB genes
por: Chang, Hung, et al.
Publicado: (2012)

A novel fusion gene involving PDGFRB and GCC2 in a chronic eosinophilic leukemia patient harboring t(2;5)(q37;q31)
por: Iriyama, Noriyoshi, et al.
Publicado: (2019)

Acute Lymphoblastic Leukemia Patient with Variant ATF7IP/PDGFRB Fusion and Favorable Response to Tyrosine Kinase Inhibitor Treatment: A Case Report
por: Zhang, Ge, et al.
Publicado: (2017)

A review on how to do hematology consults during COVID-19 pandemic
por: Sahu, Kamal Kant, et al.
Publicado: (2021)

Myeloid/Lymphoid Neoplasms with ETV6::PDGFRB Fusion Gene: A Rare Case of Poor Response to Imatinib and Possible Transformation Mechanisms from Myeloid Neoplasms of Bone Marrow to T-Cell Lymphoblastic Lymphoma Invasion in Lymph Nodes
por: Gou, Yang, et al.
Publicado: (2023)

Complete Genome Sequence of NAH7-Harboring Pseudomonas putida Strain G7
por: Varner, Paige M., et al.
Publicado: (2022)

Microglia Induce PDGFRB Expression in Glioma Cells to Enhance Their Migratory Capacity
por: Wallmann, Tatjana, et al.
Publicado: (2018)

Construction and Characterization of T7 Bacteriophages Harboring Apidaecin-Derived Sequences
por: Ludwig, Tobias, et al.
Publicado: (2022)

COVID19 infection in a patient undergoing treatment for Paroxysmal Nocturnal Hemoglobinuria (PNH) with Ravulizumab
por: Shikdar, Sufana, et al.
Publicado: (2021)

Functional Characterization of Germline Mutations in PDGFB and PDGFRB in Primary Familial Brain Calcification
por: Vanlandewijck, Michael, et al.
Publicado: (2015)

Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling
por: Arts, Florence A, et al.
Publicado: (2015)

Deregulation of kinase signaling and lymphoid development in EBF1-PDGFRB ALL leukemogenesis
por: Welsh, Seth J., et al.
Publicado: (2017)

Temperature-dependent autoactivation associated with clinical variability of PDGFRB Asn666 substitutions
por: Bredrup, Cecilie, et al.
Publicado: (2021)

Coagulopathy, endothelial dysfunction, thrombotic microangiopathy and complement activation: potential role of complement system inhibition in COVID-19
por: Wang, Xin, et al.
Publicado: (2020)

Role of Immunomodulation of BCG Therapy on AML Remission
por: Kennedy, Alice, et al.
Publicado: (2021)

Circular RNA Circ_0016760 Modulates Non-Small-Cell Lung Cancer Growth Through the miR-577/ZBTB7A Axis
por: Hao, Yanhong, et al.
Publicado: (2020)

ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation
por: Hartmann, Luise, et al.
Publicado: (2016)

Translocation of heme oxygenase-1 contributes to imatinib resistance in chronic myelogenous leukemia
por: Schaefer, Bianca, et al.
Publicado: (2017)

NDEL1-PDGFRB fusion gene in a myeloid malignancy with eosinophilia associated with resistance to tyrosine kinase inhibitors
por: Byrgazov, K, et al.
Publicado: (2017)

Cytogenetically cryptic ZMYM2-FLT3 and DIAPH1-PDGFRB gene fusions in myeloid neoplasms with eosinophilia
por: Jawhar, Mohamad, et al.
Publicado: (2017)

577. Barriers to Transitions of Care in the Detroit Young HIV Population
por: Bohler, Rynita, et al.
Publicado: (2018)

A Novel Three-Colour Fluorescence in Situ Hybridization Approach for the Detection of t(7;12)(q36;p13) in Acute Myeloid Leukaemia Reveals New Cryptic Three Way Translocation t(7;12;16)
por: Naiel, Abdulbasit, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_779fhmdnerqdo6ptfn8lhstrjq