Bacterial lectin BambL acts as a B cell superantigen

B cell superantigens crosslink conserved domains of B cell receptors (BCRs) and cause dysregulated, polyclonal B cell activation irrespective of normal BCR-antigen complementarity. The cells typically succumb to activation-induced cell death, which can impede the adaptive immune response and favor i...

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Detalles Bibliográficos
Autores principales: Frensch, Marco, Jäger, Christina, Müller, Peter F., Tadić, Annamaria, Wilhelm, Isabel, Wehrum, Sarah, Diedrich, Britta, Fischer, Beate, Meléndez, Ana Valeria, Dengjel, Joern, Eibel, Hermann, Römer, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629787/
https://www.ncbi.nlm.nih.gov/pubmed/34731252
http://dx.doi.org/10.1007/s00018-021-04009-z

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