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Instability of a liquid sheet with viscosity contrast in inertial microfluidics
ABSTRACT: Flows at moderate Reynolds numbers in inertial microfluidics enable high throughput and inertial focusing of particles and cells with relevance in biomedical applications. In the present work, we consider a viscosity-stratified three-layer flow in the inertial regime. We investigate the in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629957/ https://www.ncbi.nlm.nih.gov/pubmed/34845537 http://dx.doi.org/10.1140/epje/s10189-021-00147-1 |
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author | Patel, Kuntal Stark, Holger |
author_facet | Patel, Kuntal Stark, Holger |
author_sort | Patel, Kuntal |
collection | PubMed |
description | ABSTRACT: Flows at moderate Reynolds numbers in inertial microfluidics enable high throughput and inertial focusing of particles and cells with relevance in biomedical applications. In the present work, we consider a viscosity-stratified three-layer flow in the inertial regime. We investigate the interfacial instability of a liquid sheet surrounded by a density-matched but more viscous fluid in a channel flow. We use linear stability analysis based on the Orr–Sommerfeld equation and direct numerical simulations with the lattice Boltzmann method (LBM) to perform an extensive parameter study. Our aim is to contribute to a controlled droplet production in inertial microfluidics. In the first part, on the linear stability analysis we show that the growth rate of the fastest growing mode [Formula: see text] increases with the Reynolds number [Formula: see text] and that its wavelength [Formula: see text] is always smaller than the channel width w for sufficiently small interfacial tension [Formula: see text] . For thin sheets we find the scaling relation [Formula: see text] , where m is viscosity ratio and [Formula: see text] the sheet thickness. In contrast, for thicker sheets [Formula: see text] decreases with increasing [Formula: see text] or m due to the nearby channel walls. Examining the eigenvalue spectra, we identify Yih modes at the interface. In the second part on the LBM simulations, the thin liquid sheet develops two distinct dynamic states: waves traveling along the interface and breakup into droplets with bullet shape. For smaller flow rates and larger sheet thicknesses, we also observe ligament formation and the sheet eventually evolves irregularly. Our work gives some indication how droplet formation can be controlled with a suitable parameter set [Formula: see text] . GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version supplementary material available at 10.1140/epje/s10189-021-00147-1. |
format | Online Article Text |
id | pubmed-8629957 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-86299572021-12-15 Instability of a liquid sheet with viscosity contrast in inertial microfluidics Patel, Kuntal Stark, Holger Eur Phys J E Soft Matter Regular Article - Flowing Matter ABSTRACT: Flows at moderate Reynolds numbers in inertial microfluidics enable high throughput and inertial focusing of particles and cells with relevance in biomedical applications. In the present work, we consider a viscosity-stratified three-layer flow in the inertial regime. We investigate the interfacial instability of a liquid sheet surrounded by a density-matched but more viscous fluid in a channel flow. We use linear stability analysis based on the Orr–Sommerfeld equation and direct numerical simulations with the lattice Boltzmann method (LBM) to perform an extensive parameter study. Our aim is to contribute to a controlled droplet production in inertial microfluidics. In the first part, on the linear stability analysis we show that the growth rate of the fastest growing mode [Formula: see text] increases with the Reynolds number [Formula: see text] and that its wavelength [Formula: see text] is always smaller than the channel width w for sufficiently small interfacial tension [Formula: see text] . For thin sheets we find the scaling relation [Formula: see text] , where m is viscosity ratio and [Formula: see text] the sheet thickness. In contrast, for thicker sheets [Formula: see text] decreases with increasing [Formula: see text] or m due to the nearby channel walls. Examining the eigenvalue spectra, we identify Yih modes at the interface. In the second part on the LBM simulations, the thin liquid sheet develops two distinct dynamic states: waves traveling along the interface and breakup into droplets with bullet shape. For smaller flow rates and larger sheet thicknesses, we also observe ligament formation and the sheet eventually evolves irregularly. Our work gives some indication how droplet formation can be controlled with a suitable parameter set [Formula: see text] . GRAPHICAL ABSTRACT: [Image: see text] SUPPLEMENTARY INFORMATION: The online version supplementary material available at 10.1140/epje/s10189-021-00147-1. Springer Berlin Heidelberg 2021-11-29 2021 /pmc/articles/PMC8629957/ /pubmed/34845537 http://dx.doi.org/10.1140/epje/s10189-021-00147-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Regular Article - Flowing Matter Patel, Kuntal Stark, Holger Instability of a liquid sheet with viscosity contrast in inertial microfluidics |
title | Instability of a liquid sheet with viscosity contrast in inertial microfluidics |
title_full | Instability of a liquid sheet with viscosity contrast in inertial microfluidics |
title_fullStr | Instability of a liquid sheet with viscosity contrast in inertial microfluidics |
title_full_unstemmed | Instability of a liquid sheet with viscosity contrast in inertial microfluidics |
title_short | Instability of a liquid sheet with viscosity contrast in inertial microfluidics |
title_sort | instability of a liquid sheet with viscosity contrast in inertial microfluidics |
topic | Regular Article - Flowing Matter |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629957/ https://www.ncbi.nlm.nih.gov/pubmed/34845537 http://dx.doi.org/10.1140/epje/s10189-021-00147-1 |
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