HLA-G genetic diversity and evolutive aspects in worldwide populations

HLA-G is a promiscuous immune checkpoint molecule. The HLA-G gene presents substantial nucleotide variability in its regulatory regions. However, it encodes a limited number of proteins compared to classical HLA class I genes. We characterized the HLA-G genetic variability in 4640 individuals from 8...

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Detalles Bibliográficos
Autores principales: Castelli, Erick C., de Almeida, Bibiana S., Muniz, Yara C. N., Silva, Nayane S. B., Passos, Marília R. S., Souza, Andreia S., Page, Abigail E., Dyble, Mark, Smith, Daniel, Aguileta, Gabriela, Bertranpetit, Jaume, Migliano, Andrea B., Duarte, Yeda A. O., Scliar, Marília O., Wang, Jaqueline, Passos-Bueno, Maria Rita, Naslavsky, Michel S., Zatz, Mayana, Mendes-Junior, Celso Teixeira, Donadi, Eduardo A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8629979/
https://www.ncbi.nlm.nih.gov/pubmed/34845256
http://dx.doi.org/10.1038/s41598-021-02106-4

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