Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy

Spinocerebellar ataxia type 2 (SCA2) is an incurable and genetic neurodegenerative disorder. The disease is characterized by progressive degeneration of several brain regions, resulting in severe motor and non-motor clinical manifestations. The mutation causing SCA2 disease is an abnormal expansion...

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Detalles Bibliográficos
Autores principales: Marcelo, Adriana, Afonso, Inês T., Afonso-Reis, Ricardo, Brito, David V. C., Costa, Rafael G., Rosa, Ana, Alves-Cruzeiro, João, Ferreira, Benedita, Henriques, Carina, Nobre, Rui J., Matos, Carlos A., de Almeida, Luís Pereira, Nóbrega, Clévio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630050/
https://www.ncbi.nlm.nih.gov/pubmed/34845184
http://dx.doi.org/10.1038/s41419-021-04404-1

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