TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer

Endometrial cancer (EC) is the most common gynecological malignancy worldwide. However, the molecular mechanisms underlying EC progression are still largely unknown, and chemotherapeutic options for EC patients are currently very limited. In this study, we found that histone methyltransferase EZH2 a...

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Detalles Bibliográficos
Autores principales: Gui, Tao, Liu, Ming, Yao, Bing, Jiang, Haiqin, Yang, Dongjun, Li, Qixiang, Zeng, Xiangwei, Wang, Ying, Cao, Jian, Deng, Yexuan, Li, Xinyu, Xu, Peipei, Zhou, Liqin, Li, Dake, Wang, Zhihui, Zen, Ke, Huang, David C. S., Chen, Bing, Wan, Guiping, Zhao, Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630057/
https://www.ncbi.nlm.nih.gov/pubmed/34175897
http://dx.doi.org/10.1038/s41418-021-00824-w

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