SIRT1 coordinates with the CRL4B complex to regulate pancreatic cancer stem cells to promote tumorigenesis

Pancreatic cancer is a common malignant tumor with poor prognosis. Recently, cancer stem cells (CSCs) were identified in several solid tumors, including pancreatic cancer. Although accumulating evidence indicates that sirtuin 1 (SIRT1) exerts biological functions in various cancers, how it contribut...

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Detalles Bibliográficos
Autores principales: Leng, Shuai, Huang, Wei, Chen, Yang, Yang, Yang, Feng, Dandan, Liu, Wei, Gao, Tianyang, Ren, Yanli, Huo, Miaomiao, Zhang, Jingyao, Yang, Yunkai, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630059/
https://www.ncbi.nlm.nih.gov/pubmed/34163012
http://dx.doi.org/10.1038/s41418-021-00821-z

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