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Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)

INTRODUCTION: Despite increased risk of cognitive decline in Hispanics/Latinos, research on early risk markers of Alzheimer's disease in this group is lacking. Subjective cognitive decline (SCD) may be an early risk marker of pathological aging. We investigated associations of SCD with objectiv...

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Autores principales: Zlatar, Zvinka Z., Tarraf, Wassim, González, Kevin A., Vásquez, Priscilla M., Marquine, María J., Lipton, Richard B., Gallo, Linda C., Khambaty, Tasneem, Zeng, Donglin, Youngblood, Marston E., Estrella, Mayra L., Isasi, Carmen R., Daviglus, Martha, González, Hector M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630099/
https://www.ncbi.nlm.nih.gov/pubmed/34057776
http://dx.doi.org/10.1002/alz.12381
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author Zlatar, Zvinka Z.
Tarraf, Wassim
González, Kevin A.
Vásquez, Priscilla M.
Marquine, María J.
Lipton, Richard B.
Gallo, Linda C.
Khambaty, Tasneem
Zeng, Donglin
Youngblood, Marston E.
Estrella, Mayra L.
Isasi, Carmen R.
Daviglus, Martha
González, Hector M.
author_facet Zlatar, Zvinka Z.
Tarraf, Wassim
González, Kevin A.
Vásquez, Priscilla M.
Marquine, María J.
Lipton, Richard B.
Gallo, Linda C.
Khambaty, Tasneem
Zeng, Donglin
Youngblood, Marston E.
Estrella, Mayra L.
Isasi, Carmen R.
Daviglus, Martha
González, Hector M.
author_sort Zlatar, Zvinka Z.
collection PubMed
description INTRODUCTION: Despite increased risk of cognitive decline in Hispanics/Latinos, research on early risk markers of Alzheimer's disease in this group is lacking. Subjective cognitive decline (SCD) may be an early risk marker of pathological aging. We investigated associations of SCD with objective cognition among a diverse sample of Hispanics/Latinos living in the United States. METHODS: SCD was measured with the Everyday Cognition Short Form (ECog‐12) and cognitive performance with a standardized battery in 6125 adults aged ≥ 50 years without mild cognitive impairment or dementia (x̄(age ) = 63.2 years, 54.5% women). Regression models interrogated associations of SCD with objective global, memory, and executive function scores. RESULTS: Higher SCD was associated with lower objective global (B = −0.16, SE = 0.01), memory (B = −0.13, SE = 0.02), and executive (B = −0.13, SE = 0.02, p's < .001) function composite scores in fully adjusted models. DISCUSSION: Self‐reported SCD, using the ECog‐12, may be an indicator of concurrent objective cognition in diverse middle‐aged and older community‐dwelling Hispanics/Latinos.
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spelling pubmed-86300992022-10-14 Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA) Zlatar, Zvinka Z. Tarraf, Wassim González, Kevin A. Vásquez, Priscilla M. Marquine, María J. Lipton, Richard B. Gallo, Linda C. Khambaty, Tasneem Zeng, Donglin Youngblood, Marston E. Estrella, Mayra L. Isasi, Carmen R. Daviglus, Martha González, Hector M. Alzheimers Dement Featured Articles INTRODUCTION: Despite increased risk of cognitive decline in Hispanics/Latinos, research on early risk markers of Alzheimer's disease in this group is lacking. Subjective cognitive decline (SCD) may be an early risk marker of pathological aging. We investigated associations of SCD with objective cognition among a diverse sample of Hispanics/Latinos living in the United States. METHODS: SCD was measured with the Everyday Cognition Short Form (ECog‐12) and cognitive performance with a standardized battery in 6125 adults aged ≥ 50 years without mild cognitive impairment or dementia (x̄(age ) = 63.2 years, 54.5% women). Regression models interrogated associations of SCD with objective global, memory, and executive function scores. RESULTS: Higher SCD was associated with lower objective global (B = −0.16, SE = 0.01), memory (B = −0.13, SE = 0.02), and executive (B = −0.13, SE = 0.02, p's < .001) function composite scores in fully adjusted models. DISCUSSION: Self‐reported SCD, using the ECog‐12, may be an indicator of concurrent objective cognition in diverse middle‐aged and older community‐dwelling Hispanics/Latinos. John Wiley and Sons Inc. 2021-05-31 2022-01 /pmc/articles/PMC8630099/ /pubmed/34057776 http://dx.doi.org/10.1002/alz.12381 Text en © 2021 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Featured Articles
Zlatar, Zvinka Z.
Tarraf, Wassim
González, Kevin A.
Vásquez, Priscilla M.
Marquine, María J.
Lipton, Richard B.
Gallo, Linda C.
Khambaty, Tasneem
Zeng, Donglin
Youngblood, Marston E.
Estrella, Mayra L.
Isasi, Carmen R.
Daviglus, Martha
González, Hector M.
Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)
title Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)
title_full Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)
title_fullStr Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)
title_full_unstemmed Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)
title_short Subjective cognitive decline and objective cognition among diverse U.S. Hispanics/Latinos: Results from the Study of Latinos‐Investigation of Neurocognitive Aging (SOL‐INCA)
title_sort subjective cognitive decline and objective cognition among diverse u.s. hispanics/latinos: results from the study of latinos‐investigation of neurocognitive aging (sol‐inca)
topic Featured Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630099/
https://www.ncbi.nlm.nih.gov/pubmed/34057776
http://dx.doi.org/10.1002/alz.12381
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