BCL-XL is crucial for progression through the adenoma-to-carcinoma sequence of colorectal cancer

Evasion of apoptosis is a hallmark of cancer, which is frequently mediated by upregulation of the antiapoptotic BCL-2 family proteins. In colorectal cancer (CRC), previous work has highlighted differential antiapoptotic protein dependencies determined by the stage of the disease. While intestinal st...

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Detalles Bibliográficos
Autores principales: Ramesh, Prashanthi, Lannagan, Tamsin R. M., Jackstadt, Rene, Atencia Taboada, Lidia, Lansu, Nico, Wirapati, Pratyaksha, van Hooff, Sander R., Dekker, Danielle, Pritchard, Jessica, Kirov, Aleksandar B., van Neerven, Sanne M., Tejpar, Sabine, Kops, Geert J. P. L., Sansom, Owen J., Medema, Jan Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630104/
https://www.ncbi.nlm.nih.gov/pubmed/34117376
http://dx.doi.org/10.1038/s41418-021-00816-w

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