CircRNA circ-NNT mediates myocardial ischemia/reperfusion injury through activating pyroptosis by sponging miR-33a-5p and regulating USP46 expression

Pyroptosis has been implicated in the pathophysiology of myocardial infarction (MI) in rodents, but its contribution to reperfusion injury in MI patients is unclear. Here, we evaluated pyroptosis in MI patients in vitro and in vivo models of myocardial ischemia/reperfusion (I/R) injury. We also inve...

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Detalles Bibliográficos
Autores principales: Ye, Xiaomiao, Hang, Yanwen, Lu, Yi, Li, Dandan, Shen, Fangfang, Guan, Ping, Dong, Jian, Shi, Ludong, Hu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630116/
https://www.ncbi.nlm.nih.gov/pubmed/34845193
http://dx.doi.org/10.1038/s41420-021-00706-7

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