Mammographic texture features associated with contralateral breast cancer in the WECARE Study

To evaluate whether mammographic texture features were associated with second primary contralateral breast cancer (CBC) risk, we created a “texture risk score” using pre-treatment mammograms in a case–control study of 212 women with CBC and 223 controls with unilateral breast cancer. The texture ris...

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Detalles Bibliográficos
Autores principales: Watt, Gordon P., Knight, Julia A., Lin, Christine, Lynch, Charles F., Malone, Kathleen E., John, Esther M., Bernstein, Leslie, Brooks, Jennifer D., Reiner, Anne S., Liang, Xiaolin, Woods, Meghan, Nguyen, Tuong L., Hopper, John L., Pike, Malcolm C., Bernstein, Jonine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630158/
https://www.ncbi.nlm.nih.gov/pubmed/34845211
http://dx.doi.org/10.1038/s41523-021-00354-1
Descripción
Sumario:To evaluate whether mammographic texture features were associated with second primary contralateral breast cancer (CBC) risk, we created a “texture risk score” using pre-treatment mammograms in a case–control study of 212 women with CBC and 223 controls with unilateral breast cancer. The texture risk score was associated with CBC (odds per adjusted standard deviation = 1.25, 95% CI 1.01–1.56) after adjustment for mammographic percent density and confounders. These results support the potential of texture features for CBC risk assessment of breast cancer survivors.

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