The PIFA-initiated oxidative cyclization of 2-(3-butenyl)quinazolin-4(3H)-ones – an efficient approach to 1-(hydroxymethyl)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-ones

A regioselective method for the synthesis of 1-(hydroxymethyl)-2,3-dihydropyrrolo[1,2-a]quinazolin-5(1H)-ones – close structural analogs of naturally occurring vasicinone alkaloids – is described. The procedure is based on PIFA-initiated oxidative 5-exo-trig cyclization of 2-(3-butenyl)quinazolin-4(...

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Detalles Bibliográficos
Autores principales: Vaskevych, Alla I, Savinchuk, Nataliia O, Vaskevych, Ruslan I, Rusanov, Eduard B, Grygorenko, Oleksandr O, Vovk, Mykhailo V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2021
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630437/
https://www.ncbi.nlm.nih.gov/pubmed/34900009
http://dx.doi.org/10.3762/bjoc.17.189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630437/
https://www.ncbi.nlm.nih.gov/pubmed/34900009
http://dx.doi.org/10.3762/bjoc.17.189

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