Cargando…

The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

In the parasite Trypanosoma brucei, the causative agent of human African sleeping sickness, all mRNAs are trans-spliced to generate a common 5′ exon derived from the spliced leader (SL) RNA. Perturbations of protein translocation across the endoplasmic reticulum (ER) induce the spliced leader RNA si...

Descripción completa

Detalles Bibliográficos
Autores principales: Okalang, Uthman, Mualem Bar-Ner, Bar, Rajan, K. Shanmugha, Friedman, Nehemya, Aryal, Saurav, Egarmina, Katarina, Hope, Ronen, Khazanov, Netaly, Senderowitz, Hanoch, Alon, Assaf, Fass, Deborah, Michaeli, Shulamit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630539/
https://www.ncbi.nlm.nih.gov/pubmed/34844425
http://dx.doi.org/10.1128/mBio.02602-21