The Spliced Leader RNA Silencing (SLS) Pathway in Trypanosoma brucei Is Induced by Perturbations of Endoplasmic Reticulum, Golgi Complex, or Mitochondrial Protein Factors: Functional Analysis of SLS-Inducing Kinase PK3

In the parasite Trypanosoma brucei, the causative agent of human African sleeping sickness, all mRNAs are trans-spliced to generate a common 5′ exon derived from the spliced leader (SL) RNA. Perturbations of protein translocation across the endoplasmic reticulum (ER) induce the spliced leader RNA si...

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Detalles Bibliográficos
Autores principales: Okalang, Uthman, Mualem Bar-Ner, Bar, Rajan, K. Shanmugha, Friedman, Nehemya, Aryal, Saurav, Egarmina, Katarina, Hope, Ronen, Khazanov, Netaly, Senderowitz, Hanoch, Alon, Assaf, Fass, Deborah, Michaeli, Shulamit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630539/
https://www.ncbi.nlm.nih.gov/pubmed/34844425
http://dx.doi.org/10.1128/mBio.02602-21

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