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Induction of Mitosis Delay and Apoptosis by CDDO-TFEA in Glioblastoma Multiforme

Background: Glioblastoma multiforme (GBM) is the vicious malignant brain tumor in adults. Despite advances multi-disciplinary treatment, GBM constinues to have a poor overall survival. CDDO-trifluoroethyl-amide (CDDO-TEFA), a trifluoroethylamidederivative of CDDO, is an Nrf2/ARE pathway activator. C...

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Detalles Bibliográficos
Autores principales: Tsai, Tai-Hsin, Lieu, Ann-Shung, Huang, Tzuu-Yuan, Kwan, Aij-Lie, Lin, Chih-Lung, Hsu, Yi-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630575/
https://www.ncbi.nlm.nih.gov/pubmed/34858180
http://dx.doi.org/10.3389/fphar.2021.756228