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Granule Leakage Induces Cell-Intrinsic, Granzyme B-Mediated Apoptosis in Mast Cells

Mast cells are multifunctional immune cells scattered in tissues near blood vessels and mucosal surfaces where they mediate important reactions against parasites and contribute to the pathogenesis of allergic reactions. Serine proteases released from secretory granules upon mast cell activation cont...

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Detalles Bibliográficos
Autores principales:	Burgener, Sabrina Sofia, Brügger, Melanie, Leborgne, Nathan Georges François, Sollberger, Sophia, Basilico, Paola, Kaufmann, Thomas, Bird, Phillip Ian, Benarafa, Charaf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630627/ https://www.ncbi.nlm.nih.gov/pubmed/34858967 http://dx.doi.org/10.3389/fcell.2021.630166

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