Single-cell expression quantitative trait loci (eQTL) analysis of SLE-risk loci in lupus patient monocytes

BACKGROUND: We performed expression quantitative trait locus (eQTL) analysis in single classical (CL) and non-classical (NCL) monocytes from patients with systemic lupus erythematosus (SLE) to quantify the impact of well-established genetic risk alleles on transcription at single-cell resolution. ME...

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Detalles Bibliográficos
Autores principales: Ghodke-Puranik, Yogita, Jin, Zhongbo, Zimmerman, Kip D., Ainsworth, Hannah C., Fan, Wei, Jensen, Mark A., Dorschner, Jessica M., Vsetecka, Danielle M., Amin, Shreyasee, Makol, Ashima, Ernste, Floranne, Osborn, Thomas, Moder, Kevin, Chowdhary, Vaidehi, Langefeld, Carl D., Niewold, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630910/
https://www.ncbi.nlm.nih.gov/pubmed/34847931
http://dx.doi.org/10.1186/s13075-021-02660-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630910/
https://www.ncbi.nlm.nih.gov/pubmed/34847931
http://dx.doi.org/10.1186/s13075-021-02660-2

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