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Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance
Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss disease, is a rare vasculitis that affects small- to medium-sized vessels and has a propensity to involve the heart. Patients with cardiac involvement have a poor prognosis and usually require immunosuppressive t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631216/ https://www.ncbi.nlm.nih.gov/pubmed/34888088 http://dx.doi.org/10.18295/squmj.4.2021.038 |
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author | Al Umairi, Rashid S. Al Manei, Khalid Al Lawati, Fatma Al Mahrouqi, Yaqoob Al Balushi, Farida |
author_facet | Al Umairi, Rashid S. Al Manei, Khalid Al Lawati, Fatma Al Mahrouqi, Yaqoob Al Balushi, Farida |
author_sort | Al Umairi, Rashid S. |
collection | PubMed |
description | Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss disease, is a rare vasculitis that affects small- to medium-sized vessels and has a propensity to involve the heart. Patients with cardiac involvement have a poor prognosis and usually require immunosuppressive treatment along with corticosteroids. Cardiovascular magnetic resonance (CMR) is a non-invasive diagnostic tool for detecting cardiac involvement and guiding the management plan. We report a 39-year-old male patient with a known history of bronchial asthma who was referred to the chest clinic at a tertiary hospital in 2019 for further assessment of persistent lung parenchymal changes on chest computed tomography. Given the clinical context of the patient and the radiological findings, EGPA was suspected and confirmed with a lung biopsy. CMR was performed for further assessment, which confirmed cardiac involvement. The patient was started on prednisolone and azathioprine and showed significant radiological and clinical improvement. |
format | Online Article Text |
id | pubmed-8631216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-86312162021-12-08 Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance Al Umairi, Rashid S. Al Manei, Khalid Al Lawati, Fatma Al Mahrouqi, Yaqoob Al Balushi, Farida Sultan Qaboos Univ Med J Case Report Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss disease, is a rare vasculitis that affects small- to medium-sized vessels and has a propensity to involve the heart. Patients with cardiac involvement have a poor prognosis and usually require immunosuppressive treatment along with corticosteroids. Cardiovascular magnetic resonance (CMR) is a non-invasive diagnostic tool for detecting cardiac involvement and guiding the management plan. We report a 39-year-old male patient with a known history of bronchial asthma who was referred to the chest clinic at a tertiary hospital in 2019 for further assessment of persistent lung parenchymal changes on chest computed tomography. Given the clinical context of the patient and the radiological findings, EGPA was suspected and confirmed with a lung biopsy. CMR was performed for further assessment, which confirmed cardiac involvement. The patient was started on prednisolone and azathioprine and showed significant radiological and clinical improvement. Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2021-11 2021-11-25 /pmc/articles/PMC8631216/ /pubmed/34888088 http://dx.doi.org/10.18295/squmj.4.2021.038 Text en © Copyright 2021, Sultan Qaboos University Medical Journal, All Rights Reserved https://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nd/4.0/) . |
spellingShingle | Case Report Al Umairi, Rashid S. Al Manei, Khalid Al Lawati, Fatma Al Mahrouqi, Yaqoob Al Balushi, Farida Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance |
title | Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance |
title_full | Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance |
title_fullStr | Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance |
title_full_unstemmed | Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance |
title_short | Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance |
title_sort | cardiac involvement in eosinophilic granulomatosis with polyangiitis (churg-strauss disease): the role of cardiovascular magnetic resonance |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631216/ https://www.ncbi.nlm.nih.gov/pubmed/34888088 http://dx.doi.org/10.18295/squmj.4.2021.038 |
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