Cargando…

Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance

Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss disease, is a rare vasculitis that affects small- to medium-sized vessels and has a propensity to involve the heart. Patients with cardiac involvement have a poor prognosis and usually require immunosuppressive t...

Descripción completa

Detalles Bibliográficos
Autores principales: Al Umairi, Rashid S., Al Manei, Khalid, Al Lawati, Fatma, Al Mahrouqi, Yaqoob, Al Balushi, Farida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631216/
https://www.ncbi.nlm.nih.gov/pubmed/34888088
http://dx.doi.org/10.18295/squmj.4.2021.038
_version_ 1784607508364525568
author Al Umairi, Rashid S.
Al Manei, Khalid
Al Lawati, Fatma
Al Mahrouqi, Yaqoob
Al Balushi, Farida
author_facet Al Umairi, Rashid S.
Al Manei, Khalid
Al Lawati, Fatma
Al Mahrouqi, Yaqoob
Al Balushi, Farida
author_sort Al Umairi, Rashid S.
collection PubMed
description Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss disease, is a rare vasculitis that affects small- to medium-sized vessels and has a propensity to involve the heart. Patients with cardiac involvement have a poor prognosis and usually require immunosuppressive treatment along with corticosteroids. Cardiovascular magnetic resonance (CMR) is a non-invasive diagnostic tool for detecting cardiac involvement and guiding the management plan. We report a 39-year-old male patient with a known history of bronchial asthma who was referred to the chest clinic at a tertiary hospital in 2019 for further assessment of persistent lung parenchymal changes on chest computed tomography. Given the clinical context of the patient and the radiological findings, EGPA was suspected and confirmed with a lung biopsy. CMR was performed for further assessment, which confirmed cardiac involvement. The patient was started on prednisolone and azathioprine and showed significant radiological and clinical improvement.
format Online
Article
Text
id pubmed-8631216
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences
record_format MEDLINE/PubMed
spelling pubmed-86312162021-12-08 Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance Al Umairi, Rashid S. Al Manei, Khalid Al Lawati, Fatma Al Mahrouqi, Yaqoob Al Balushi, Farida Sultan Qaboos Univ Med J Case Report Eosinophilic granulomatosis with polyangiitis (EGPA), previously known as Churg-Strauss disease, is a rare vasculitis that affects small- to medium-sized vessels and has a propensity to involve the heart. Patients with cardiac involvement have a poor prognosis and usually require immunosuppressive treatment along with corticosteroids. Cardiovascular magnetic resonance (CMR) is a non-invasive diagnostic tool for detecting cardiac involvement and guiding the management plan. We report a 39-year-old male patient with a known history of bronchial asthma who was referred to the chest clinic at a tertiary hospital in 2019 for further assessment of persistent lung parenchymal changes on chest computed tomography. Given the clinical context of the patient and the radiological findings, EGPA was suspected and confirmed with a lung biopsy. CMR was performed for further assessment, which confirmed cardiac involvement. The patient was started on prednisolone and azathioprine and showed significant radiological and clinical improvement. Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2021-11 2021-11-25 /pmc/articles/PMC8631216/ /pubmed/34888088 http://dx.doi.org/10.18295/squmj.4.2021.038 Text en © Copyright 2021, Sultan Qaboos University Medical Journal, All Rights Reserved https://creativecommons.org/licenses/by-nd/4.0/This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nd/4.0/) .
spellingShingle Case Report
Al Umairi, Rashid S.
Al Manei, Khalid
Al Lawati, Fatma
Al Mahrouqi, Yaqoob
Al Balushi, Farida
Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance
title Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance
title_full Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance
title_fullStr Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance
title_full_unstemmed Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance
title_short Cardiac Involvement in Eosinophilic Granulomatosis with Polyangiitis (Churg-Strauss Disease): The role of cardiovascular magnetic resonance
title_sort cardiac involvement in eosinophilic granulomatosis with polyangiitis (churg-strauss disease): the role of cardiovascular magnetic resonance
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631216/
https://www.ncbi.nlm.nih.gov/pubmed/34888088
http://dx.doi.org/10.18295/squmj.4.2021.038
work_keys_str_mv AT alumairirashids cardiacinvolvementineosinophilicgranulomatosiswithpolyangiitischurgstraussdiseasetheroleofcardiovascularmagneticresonance
AT almaneikhalid cardiacinvolvementineosinophilicgranulomatosiswithpolyangiitischurgstraussdiseasetheroleofcardiovascularmagneticresonance
AT allawatifatma cardiacinvolvementineosinophilicgranulomatosiswithpolyangiitischurgstraussdiseasetheroleofcardiovascularmagneticresonance
AT almahrouqiyaqoob cardiacinvolvementineosinophilicgranulomatosiswithpolyangiitischurgstraussdiseasetheroleofcardiovascularmagneticresonance
AT albalushifarida cardiacinvolvementineosinophilicgranulomatosiswithpolyangiitischurgstraussdiseasetheroleofcardiovascularmagneticresonance