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Integrative Analysis of Epigenome and Transcriptome Data Reveals Aberrantly Methylated Promoters and Enhancers in Hepatocellular Carcinoma

DNA methylation is a key transcription regulator, whose aberration was ubiquitous and important in most cancers including hepatocellular carcinoma (HCC). Whole-genome bisulfite sequencing (WGBS) was conducted for comparison of DNA methylation in tumor and adjacent tissues from 33 HCC patients, accom...

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Detalles Bibliográficos
Autores principales: Huang, Peng, Xu, Mengxiang, Han, Haijun, Zhao, Xinyi, Li, Ming D., Yang, Zhongli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631276/
https://www.ncbi.nlm.nih.gov/pubmed/34858848
http://dx.doi.org/10.3389/fonc.2021.769390