Cargando…

EMS1/DLL4-Notch Signaling Axis Augments Cell Cycle-Mediated Tumorigenesis and Progress in Human Adrenocortical Carcinoma

Adrenocortical carcinoma (ACC) is a rare malignant neoplasm that is prone to local invasion and metastasis. Meanwhile, overexpressed endothelial cell-specific molecule 1 (ESM1) is closely related to tumorigenesis of multitudinous tumors. However, the prognosis value and biological function of ESM1 i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yu-Gang, Wang, Ya, Zhu, Rui-Juan, Tang, Kai, Tang, Xian-Bin, Su, Xiao-Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631517/ https://www.ncbi.nlm.nih.gov/pubmed/34858850 http://dx.doi.org/10.3389/fonc.2021.771579

Ejemplares similares

Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo
por: Geffers, Insa, et al.
Publicado: (2007)

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo
por: Preuße, Kristina, et al.
Publicado: (2015)

Feedback regulation of Notch signaling and myogenesis connected by MyoD–Dll1 axis
por: Zhang, Haifeng, et al.
Publicado: (2021)

The ectodomains determine ligand function in vivo and selectivity of DLL1 and DLL4 toward NOTCH1 and NOTCH2 in vitro
por: Tveriakhina, Lena, et al.
Publicado: (2018)

Inhibition of Dll4/Notch1 pathway promotes angiogenesis of Masquelet’s induced membrane in rats
por: Tang, Qian, et al.
Publicado: (2018)

The E3 ubiquitin ligase HUWE1 acts through the N‐Myc‐DLL1‐NOTCH1 signaling axis to suppress glioblastoma progression
por: Yuan, Ye, et al.
Publicado: (2022)

Distinct expression patterns of Notch ligands, Dll1 and Dll4, in normal and inflamed mice intestine
por: Shimizu, Hiromichi, et al.
Publicado: (2014)

Expressions and Prognostic Values of Notch3 and DLL4 in Human Breast Cancer
por: Wang, Lin, et al.
Publicado: (2023)

Slug regulates the Dll4-Notch-VEGFR2 axis to control endothelial cell activation and angiogenesis
por: Hultgren, Nan W., et al.
Publicado: (2020)

Crenigacestat, a selective NOTCH1 inhibitor, reduces intrahepatic cholangiocarcinoma progression by blocking VEGFA/DLL4/MMP13 axis
por: Mancarella, Serena, et al.
Publicado: (2020)

Therapeutic promise and challenges of targeting DLL4/NOTCH1
por: Yan, Minhong
Publicado: (2011)

Maintenance of Bone Homeostasis by DLL1‐Mediated Notch Signaling
por: Muguruma, Yukari, et al.
Publicado: (2017)

DAPT, a γ-Secretase Inhibitor, Suppresses Tumorigenesis, and Progression of Growth Hormone-Producing Adenomas by Targeting Notch Signaling
por: Feng, Jie, et al.
Publicado: (2019)

Dll4/Notch1 signalling pathway is required in collective invasion of salivary adenoid cystic carcinoma
por: Wang, Ke, et al.
Publicado: (2022)

Dll4/Notch1 signalling pathway is required in collective invasion of salivary adenoid cystic carcinoma
por: Wang, Ke, et al.
Publicado: (2021)

KSHV Manipulates Notch Signaling by DLL4 and JAG1 to Alter Cell Cycle Genes in Lymphatic Endothelia
por: Emuss, Victoria, et al.
Publicado: (2009)

Dll1 Can Function as a Ligand of Notch1 and Notch2 in the Thymic Epithelium
por: Hirano, Ken-ichi, et al.
Publicado: (2022)

Hypoxia-induced AFAP1L1 regulates pathological neovascularization via the YAP-DLL4-NOTCH axis
por: Ren, Jun-Song, et al.
Publicado: (2023)

Dll4-Notch signaling as a therapeutic target in tumor angiogenesis
por: Kuhnert, Frank, et al.
Publicado: (2011)

MPDZ promotes DLL4-induced Notch signaling during angiogenesis
por: Tetzlaff, Fabian, et al.
Publicado: (2018)

DLL3 regulates Notch signaling in small cell lung cancer
por: Kim, Jun W., et al.
Publicado: (2022)

Dihydroartemisinin Suppresses the Tumorigenesis and Cycle Progression of Colorectal Cancer by Targeting CDK1/CCNB1/PLK1 Signaling
por: Yi, You-Cai, et al.
Publicado: (2021)

CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle
por: Huang, Yu-gang, et al.
Publicado: (2022)

Spatial patterning of the Notch ligand Dll4 controls endothelial sprouting in vitro
por: Tiemeijer, L. A., et al.
Publicado: (2018)

Targeting the DLL/Notch Signaling Pathway in Cancer: Challenges and Advances in Clinical Development
por: You, Weon-Kyoo, et al.
Publicado: (2023)

Gene Expression and Regulation in Adrenocortical Tumorigenesis
por: Fonseca, Annabelle L., et al.
Publicado: (2012)

DLL3 Is a Prognostic and Potentially Predictive Biomarker for Immunotherapy Linked to PD/PD-L Axis and NOTCH1 in Pancreatic Cancer
por: Lacalle-Gonzalez, Carlos, et al.
Publicado: (2023)

Spatiotemporal oscillations of Notch1, Dll1 and NICD are coordinated across the mouse PSM
por: Bone, Robert A., et al.
Publicado: (2014)

The Notch ligand DLL1 exerts carcinogenic features in human breast cancer cells
por: Sales-Dias, Joana, et al.
Publicado: (2019)

Estrogen-dependent DLL1-mediated Notch signaling promotes luminal breast cancer
por: Kumar, Sushil, et al.
Publicado: (2018)

Activity of the mouse Notch ligand DLL1 is sensitive to C-terminal tagging in vivo
por: Schuster-Gossler, Karin, et al.
Publicado: (2021)

The potential value of Notch1 and DLL1 in the diagnosis and prognosis of patients with active TB
por: Xie, Jinling, et al.
Publicado: (2023)

Tryptanthrin inhibits tumor angiogenesis via Notch/Dll4 signaling pathway in zebrafish
por: Lin, Meimei, et al.
Publicado: (2023)

DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression
por: Xu, Kun, et al.
Publicado: (2022)

Methylation-driven gene DLL3 is a potential prognostic biomarker in ocular melanoma correlating with metastasis
por: Yang, Ludi, et al.
Publicado: (2022)

NOTCH2/NOTCH3/DLL3/MAML1/ADAM17 signaling network is associated with ovarian cancer
por: Jia, Dongyu, et al.
Publicado: (2019)

The Role of Dll4/Notch Signaling in Normal and Pathological Ocular Angiogenesis: Dll4 Controls Blood Vessel Sprouting and Vessel Remodeling in Normal and Pathological Conditions
por: Lobov, Ivan, et al.
Publicado: (2018)

Hepatocyte Growth Factor Overexpression Slows the Progression of 4NQO-Induced Oral Tumorigenesis
por: He, Xiaoxi, et al.
Publicado: (2021)

Corrigendum: DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression
por: Xu, Kun, et al.
Publicado: (2023)

Specific NOTCH1 antibody targets DLL4-induced proliferation, migration, and angiogenesis in NOTCH1-mutated CLL cells
por: López-Guerra, Mónica, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_v5a42ldkqnirf8fro5vl5g1ejd