Cargando…
Dual Targeting of Multiple Myeloma Stem Cells and Myeloid-Derived Suppressor Cells for Treatment of Chemotherapy-Resistant Multiple Myeloma
Here we review the insights and lessons learned from early clinical trials of T-cell engaging bispecific antibodies (BsABs) as a new class of biotherapeutic drug candidates with clinical impact potential for the treatment of multiple myeloma (MM). BsABs are capable of redirecting host T-cell cytotox...
Autor principal: | Uckun, Fatih M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631522/ https://www.ncbi.nlm.nih.gov/pubmed/34858838 http://dx.doi.org/10.3389/fonc.2021.760382 |
Ejemplares similares
-
Myeloid-Derived Suppressor Cells in Multiple Myeloma: Pre-Clinical Research and Translational Opportunities
por: Botta, Cirino, et al.
Publicado: (2014) -
Cancer drug resistance in multiple myeloma
por: Uckun, Fatih M.
Publicado: (2022) -
Overcoming the Immunosuppressive Tumor Microenvironment in Multiple Myeloma
por: Uckun, Fatih M.
Publicado: (2021) -
Dual Targeting to Overcome Current Challenges in Multiple Myeloma CAR T-Cell Treatment
por: van der Schans, Jort J., et al.
Publicado: (2020) -
Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma
por: Binsfeld, Marilène, et al.
Publicado: (2016)