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Preexisting memory CD4(+) T cells contribute to the primary response in an HIV-1 vaccine trial
Naive and memory CD4(+) T cells reactive with human immunodeficiency virus type 1 (HIV-1) are detectable in unexposed, unimmunized individuals. The contribution of preexisting CD4(+) T cells to a primary immune response was investigated in 20 HIV-1–seronegative volunteers vaccinated with an HIV-1 en...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Clinical Investigation
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631594/ https://www.ncbi.nlm.nih.gov/pubmed/34850742 http://dx.doi.org/10.1172/JCI150823 |