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Preexisting memory CD4(+) T cells contribute to the primary response in an HIV-1 vaccine trial

Naive and memory CD4(+) T cells reactive with human immunodeficiency virus type 1 (HIV-1) are detectable in unexposed, unimmunized individuals. The contribution of preexisting CD4(+) T cells to a primary immune response was investigated in 20 HIV-1–seronegative volunteers vaccinated with an HIV-1 en...

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Detalles Bibliográficos
Autores principales:	Campion, Suzanne L., Brenna, Elena, Thomson, Elaine, Fischer, Will, Ladell, Kristin, McLaren, James E., Price, David A., Frahm, Nicole, McElrath, Juliana M., Cohen, Kristen W., Maenza, Janine R., Walsh, Stephen R., Baden, Lindsey R., Haynes, Barton F., Korber, Bette, Borrow, Persephone, McMichael, Andrew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2021
Materias:	Concise Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631594/ https://www.ncbi.nlm.nih.gov/pubmed/34850742 http://dx.doi.org/10.1172/JCI150823

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