Cargando…
The cellular prion protein interacts with and promotes the activity of Na,K-ATPases
The prion protein (PrP) is best known for its ability to cause fatal neurodegenerative diseases in humans and animals. Here, we revisited its molecular environment in the brain using a well-developed affinity-capture mass spectrometry workflow that offers robust relative quantitation. The analysis c...
Autores principales: | Williams, Declan, Mehrabian, Mohadeseh, Arshad, Hamza, Eid, Shehab, Sackmann, Christopher, Zhao, Wenda, Wang, Xinzhu, Ghodrati, Farinaz, Verkuyl, Claire E., Watts, Joel C., Schmitt-Ulms, Gerold |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631662/ https://www.ncbi.nlm.nih.gov/pubmed/34847154 http://dx.doi.org/10.1371/journal.pone.0258682 |
Ejemplares similares
-
Cardiac glycoside-mediated turnover of Na, K-ATPases as a rational approach to reducing cell surface levels of the cellular prion protein
por: Mehrabian, Mohadeseh, et al.
Publicado: (2022) -
The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling
por: Ghodrati, Farinaz, et al.
Publicado: (2018) -
Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein
por: Eid, Shehab, et al.
Publicado: (2022) -
An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition
por: Mehrabian, Mohadeseh, et al.
Publicado: (2014) -
NCAM1 Polysialylation: The Prion Protein's Elusive Reason for Being?
por: Mehrabian, Mohadeseh, et al.
Publicado: (2016)