GMP Compliant Synthesis of [(18)F]Canagliflozin, a Novel PET Tracer for the Sodium–Glucose Cotransporter 2

[Image: see text] Inhibition of the sodium–glucose cotransporter 2 (SGLT2) by canagliflozin in type 2 diabetes mellitus results in large between-patient variability in clinical response. To better understand this variability, the positron emission tomography (PET) tracer [(18)F]canagliflozin was dev...

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Detalles Bibliográficos
Autores principales: van der Hoek, Sjoukje, Antunes, Inês F., Attia, Khaled A., Jacquet, Olivier, Heeres, Andre, Bulthuis, Marian, Zijlma, Rolf, Boersma, Hendrikus H., van Goor, Harry, Visser, Ton J., Heerspink, Hiddo J. L., Elsinga, Philip H., Stevens, Jasper
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631709/
https://www.ncbi.nlm.nih.gov/pubmed/34748702
http://dx.doi.org/10.1021/acs.jmedchem.1c01269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631709/
https://www.ncbi.nlm.nih.gov/pubmed/34748702
http://dx.doi.org/10.1021/acs.jmedchem.1c01269

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