Cargando…

HK2 Is a Crucial Downstream Regulator of miR-148a for the Maintenance of Sphere-Forming Property and Cisplatin Resistance in Cervical Cancer Cells

The acquisition of cancer stem-like properties is believed to be responsible for cancer metastasis and therapeutic resistance in cervical cancer (CC). CC tissues display a high expression level of hexokinase 2 (HK2), which is critical for the proliferation and migration of CC cells. However, little...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Hao, Hou, Hui, Zhao, Haiping, Yu, Tianwei, Hu, Yuchong, Hu, Yue, Guo, Junmei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8631922/ https://www.ncbi.nlm.nih.gov/pubmed/34858863 http://dx.doi.org/10.3389/fonc.2021.794015

Ejemplares similares

LncRNA OTUD6B-AS1 Induces Cisplatin Resistance in Cervical Cancer Cells Through Up-Regulating Cyclin D2 via miR-206
por: Hou, Hui, et al.
Publicado: (2021)

The Roles of HK2 on Tumorigenesis of Cervical Cancer
por: Liu, Chunyan, et al.
Publicado: (2019)

The Role of Mir-148a in Cancer
por: Li, Yue, et al.
Publicado: (2016)

Epidrug Modulated Expression of MiR-152 and MiR-148a Reverse Cisplatin Resistance in Ovarian Cancer Cells: An Experimental In-vitro Study
por: Khajehnoori, Sahel, et al.
Publicado: (2020)

PI3Kβ downstream of GPCRs – crucial partners in oncogenesis
por: Dbouk, Hashem A., et al.
Publicado: (2012)

miR-148 Regulates Mitf in Melanoma Cells
por: Haflidadóttir, Benedikta S., et al.
Publicado: (2010)

CTRP3 attenuates inflammation, oxidative and cell death in cisplatin induced HK-2 cells
por: Zou, Chenglin, et al.
Publicado: (2023)

Downstream Effectors of ILK in Cisplatin-Resistant Ovarian Cancer
por: Reyes-González, Jeyshka M., et al.
Publicado: (2020)

ATPase copper transporter A, negatively regulated by miR‐148a‐3p, contributes to cisplatin resistance in breast cancer cells
por: Yu, Ze, et al.
Publicado: (2020)

Circulating miR-148b and miR-133a as biomarkers for breast cancer detection
por: Shen, Jie, et al.
Publicado: (2014)

miR-148 family members are putative biomarkers for sepsis
por: Dong, Lei, et al.
Publicado: (2019)

Quantitative proteomic analysis of sphere-forming stem-like oral cancer cells
por: Misuno, Kaori, et al.
Publicado: (2013)

A study of association between expression of hOGG1, VDAC1, HK-2 and cervical carcinoma
por: Guo-Qing, Peng, et al.
Publicado: (2010)

Effect of lentivirus-mediated shRNA inactivation of HK1, HK2, and HK3 genes in colorectal cancer and melanoma cells
por: Kudryavtseva, Anna V., et al.
Publicado: (2016)

EBP1: A crucial growth regulator downstream of receptor kinases across kingdoms
por: Stegmann, Martin
Publicado: (2018)

Cisplatin-resistant cells in malignant pleural mesothelioma cell lines show ALDH(high)CD44(+) phenotype and sphere-forming capacity
por: Cortes-Dericks, Lourdes, et al.
Publicado: (2014)

LncRNA SNHG12 regulates the radiosensitivity of cervical cancer through the miR-148a/CDK1 pathway
por: Wang, Chen, et al.
Publicado: (2020)

miR-148a is a downstream effector of X-box-binding protein 1 that silences Wnt10b during adipogenesis of 3T3-L1 cells
por: Cho, Yoon Mi, et al.
Publicado: (2016)

Correction: A study of association between expression of hOGG1, VDAC1, HK-2 and cervical carcinoma
por: Guo-Qing, Peng, et al.
Publicado: (2011)

Identification of the xenograft and its ascendant sphere-forming cell line as belonging to EBV-induced lymphoma, and characterization of the status of sphere-forming cells
por: Dolgova, Evgeniya V., et al.
Publicado: (2019)

MiR-148a inhibits angiogenesis by targeting ERBB3()
por: Yu, Jing, et al.
Publicado: (2011)

miR‐148a suppresses inflammation in lipopolysaccharide‐induced endometritis
por: Jiang, Kangfeng, et al.
Publicado: (2019)

Pervasive RNA folding is crucial for narnavirus genome maintenance
por: Fukuda, Makiha, et al.
Publicado: (2023)

Conformal symmetry breaking operators for differential forms on spheres
por: Kobayashi, Toshiyuki, et al.
Publicado: (2016)

Antibiotics inhibit sphere-forming ability in suspension culture
por: Relier, Sébastien, et al.
Publicado: (2016)

Involvement of EZH2 in aerobic glycolysis of prostate cancer through miR-181b/HK2 axis
por: Tao, Tao, et al.
Publicado: (2017)

LncRNA HOTAIRM1 is involved in the progression of acute myeloid leukemia through targeting miR-148b
por: Hu, Ning, et al.
Publicado: (2019)

LncRNA-DANCR Interferes With miR-125b-5p/HK2 Axis to Desensitize Colon Cancer Cells to Cisplatin vis Activating Anaerobic Glycolysis
por: Shi, Huijuan, et al.
Publicado: (2020)

Sphere-Formation Assay: Three-Dimensional in vitro Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells
por: Bahmad, Hisham F., et al.
Publicado: (2018)

Role of miR-148a in Hepatitis B Associated Hepatocellular Carcinoma
por: Yuan, Ke, et al.
Publicado: (2012)

Identification of miR-148a as a novel regulator of cholesterol metabolism
por: Goedeke, Leigh, et al.
Publicado: (2015)

The Tumor Suppressive mir-148a Is Epigenetically Inactivated in Classical Hodgkin Lymphoma
por: Paczkowska, Julia, et al.
Publicado: (2020)

Molecular mechanisms of cisplatin resistance in cervical cancer
por: Zhu, Haiyan, et al.
Publicado: (2016)

Retraction Note to: LncRNA SNHG12 regulates the radiosensitivity of cervical cancer through the miR-148a/CDK1 pathway
por: Wang, Chen, et al.
Publicado: (2022)

Akt Phosphorylates HK-II at Thr-473 and Increases Mitochondrial HK-II Association to Protect Cardiomyocytes
por: Roberts, David J., et al.
Publicado: (2013)

Activin B functions downstream of BRCA1 in stem cell maintenance
por: Murray, MM, et al.
Publicado: (2010)

Urine-Derived Stem Cell-Secreted Klotho Plays a Crucial Role in the HK-2 Fibrosis Model by Inhibiting the TGF-β Signaling Pathway
por: Kim, Sang-Heon, et al.
Publicado: (2022)

Downstream Targets of Lmo4 Are Modulated by Cisplatin in the Inner Ear of Wistar Rats
por: Jamesdaniel, Samson
Publicado: (2014)

miR-202 functions as a tumor suppressor in hepatocellular carcinoma by targeting HK2
por: Wang, Jiangang, et al.
Publicado: (2020)

miR-148b-3p, miR-190b, and miR-429 Regulate Cell Progression and Act as Potential Biomarkers for Breast Cancer
por: Dai, Wenzhu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_lgdavdbummrm7jbpqtds59hie0