All genera of Flaviviridae host a conserved Xrn1-resistant RNA motif

After infection by flaviviruses like Zika and West Nile virus, eukaryotic hosts employ the well-conserved endoribonuclease Xrn1 to degrade the viral genomic RNA. Within the 3ʹ untranslated regions, this enzyme encounters intricate Xrn1-resistant structures. This results in the accumulation of subgen...

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Detalles Bibliográficos
Autores principales: Dilweg, Ivar W., Savina, Anya, Köthe, Susanne, Gultyaev, Alexander P., Bredenbeek, Peter J., Olsthoorn, René C.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632102/
https://www.ncbi.nlm.nih.gov/pubmed/33858294
http://dx.doi.org/10.1080/15476286.2021.1907044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632102/
https://www.ncbi.nlm.nih.gov/pubmed/33858294
http://dx.doi.org/10.1080/15476286.2021.1907044

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