Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach

The treatment of cancer of unknown primary (CUP) is a huge challenge for clinicians. Gene expression profiling can help identify the tissue origin of tumors by detecting the expression levels of specific genes in tumor tissues. Herein, we report four CUP cases. All of them have been successfully ide...

Descripción completa

Detalles Bibliográficos
Autores principales: Pu, Xingxiang, Yang, Sa, Xu, Yan, Chen, Bolin, Wang, Qianzhi, Gong, Qian, Wu, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632144/
https://www.ncbi.nlm.nih.gov/pubmed/34858803
http://dx.doi.org/10.3389/fonc.2021.702887
_version_ 1784607697281220608
author Pu, Xingxiang
Yang, Sa
Xu, Yan
Chen, Bolin
Wang, Qianzhi
Gong, Qian
Wu, Lin
author_facet Pu, Xingxiang
Yang, Sa
Xu, Yan
Chen, Bolin
Wang, Qianzhi
Gong, Qian
Wu, Lin
author_sort Pu, Xingxiang
collection PubMed
description The treatment of cancer of unknown primary (CUP) is a huge challenge for clinicians. Gene expression profiling can help identify the tissue origin of tumors by detecting the expression levels of specific genes in tumor tissues. Herein, we report four CUP cases. All of them have been successfully identified with the corresponding primary tumor sites through gene expression profiling analysis. Then all patients received accurate treatment, providing reference to guide therapeutic decisions to treat CUP tumors in the future.
format Online
Article
Text
id pubmed-8632144
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-86321442021-12-01 Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach Pu, Xingxiang Yang, Sa Xu, Yan Chen, Bolin Wang, Qianzhi Gong, Qian Wu, Lin Front Oncol Oncology The treatment of cancer of unknown primary (CUP) is a huge challenge for clinicians. Gene expression profiling can help identify the tissue origin of tumors by detecting the expression levels of specific genes in tumor tissues. Herein, we report four CUP cases. All of them have been successfully identified with the corresponding primary tumor sites through gene expression profiling analysis. Then all patients received accurate treatment, providing reference to guide therapeutic decisions to treat CUP tumors in the future. Frontiers Media S.A. 2021-11-11 /pmc/articles/PMC8632144/ /pubmed/34858803 http://dx.doi.org/10.3389/fonc.2021.702887 Text en Copyright © 2021 Pu, Yang, Xu, Chen, Wang, Gong and Wu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Pu, Xingxiang
Yang, Sa
Xu, Yan
Chen, Bolin
Wang, Qianzhi
Gong, Qian
Wu, Lin
Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_full Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_fullStr Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_full_unstemmed Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_short Case Report: Tissue Origin Identification for Cancer of Unknown Primary: Gene Expression Profiling Approach
title_sort case report: tissue origin identification for cancer of unknown primary: gene expression profiling approach
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632144/
https://www.ncbi.nlm.nih.gov/pubmed/34858803
http://dx.doi.org/10.3389/fonc.2021.702887
work_keys_str_mv AT puxingxiang casereporttissueoriginidentificationforcancerofunknownprimarygeneexpressionprofilingapproach
AT yangsa casereporttissueoriginidentificationforcancerofunknownprimarygeneexpressionprofilingapproach
AT xuyan casereporttissueoriginidentificationforcancerofunknownprimarygeneexpressionprofilingapproach
AT chenbolin casereporttissueoriginidentificationforcancerofunknownprimarygeneexpressionprofilingapproach
AT wangqianzhi casereporttissueoriginidentificationforcancerofunknownprimarygeneexpressionprofilingapproach
AT gongqian casereporttissueoriginidentificationforcancerofunknownprimarygeneexpressionprofilingapproach
AT wulin casereporttissueoriginidentificationforcancerofunknownprimarygeneexpressionprofilingapproach

Ejemplares similares