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Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020

Influenza strains circulating among swine populations can cause outbreaks in humans. In October 2020, we detected a variant influenza A subtype H1N2 of swine origin in a person in Alberta, Canada. We initiated a public health, veterinary, and laboratory investigation to identify the source of the in...

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Autores principales: Kanji, Jamil N., Pabbaraju, Kanti, Croxen, Matthew, Detmer, Susan, Bastien, Nathalie, Li, Yan, Majer, Anna, Keshwani, Hussein, Zelyas, Nathan, Achebe, Ifeoma, Jones, Corinne, Rutz, Maureen, Jacobs, Angela, Lehman, Keith, Hinshaw, Deena, Tipples, Graham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632177/
https://www.ncbi.nlm.nih.gov/pubmed/34808085
http://dx.doi.org/10.3201/eid2712.210298
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author Kanji, Jamil N.
Pabbaraju, Kanti
Croxen, Matthew
Detmer, Susan
Bastien, Nathalie
Li, Yan
Majer, Anna
Keshwani, Hussein
Zelyas, Nathan
Achebe, Ifeoma
Jones, Corinne
Rutz, Maureen
Jacobs, Angela
Lehman, Keith
Hinshaw, Deena
Tipples, Graham
author_facet Kanji, Jamil N.
Pabbaraju, Kanti
Croxen, Matthew
Detmer, Susan
Bastien, Nathalie
Li, Yan
Majer, Anna
Keshwani, Hussein
Zelyas, Nathan
Achebe, Ifeoma
Jones, Corinne
Rutz, Maureen
Jacobs, Angela
Lehman, Keith
Hinshaw, Deena
Tipples, Graham
author_sort Kanji, Jamil N.
collection PubMed
description Influenza strains circulating among swine populations can cause outbreaks in humans. In October 2020, we detected a variant influenza A subtype H1N2 of swine origin in a person in Alberta, Canada. We initiated a public health, veterinary, and laboratory investigation to identify the source of the infection and determine whether it had spread. We identified the probable source as a local pig farm where a household contact of the index patient worked. Phylogenetic analysis revealed that the isolate closely resembled strains found at that farm in 2017. Retrospective and prospective surveillance using molecular testing did not identify any secondary cases among 1,532 persons tested in the surrounding area. Quick collaboration between human and veterinary public health practitioners in this case enabled a rapid response to a potential outbreak.
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spelling pubmed-86321772021-12-01 Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020 Kanji, Jamil N. Pabbaraju, Kanti Croxen, Matthew Detmer, Susan Bastien, Nathalie Li, Yan Majer, Anna Keshwani, Hussein Zelyas, Nathan Achebe, Ifeoma Jones, Corinne Rutz, Maureen Jacobs, Angela Lehman, Keith Hinshaw, Deena Tipples, Graham Emerg Infect Dis Research Influenza strains circulating among swine populations can cause outbreaks in humans. In October 2020, we detected a variant influenza A subtype H1N2 of swine origin in a person in Alberta, Canada. We initiated a public health, veterinary, and laboratory investigation to identify the source of the infection and determine whether it had spread. We identified the probable source as a local pig farm where a household contact of the index patient worked. Phylogenetic analysis revealed that the isolate closely resembled strains found at that farm in 2017. Retrospective and prospective surveillance using molecular testing did not identify any secondary cases among 1,532 persons tested in the surrounding area. Quick collaboration between human and veterinary public health practitioners in this case enabled a rapid response to a potential outbreak. Centers for Disease Control and Prevention 2021-12 /pmc/articles/PMC8632177/ /pubmed/34808085 http://dx.doi.org/10.3201/eid2712.210298 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Kanji, Jamil N.
Pabbaraju, Kanti
Croxen, Matthew
Detmer, Susan
Bastien, Nathalie
Li, Yan
Majer, Anna
Keshwani, Hussein
Zelyas, Nathan
Achebe, Ifeoma
Jones, Corinne
Rutz, Maureen
Jacobs, Angela
Lehman, Keith
Hinshaw, Deena
Tipples, Graham
Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020
title Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020
title_full Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020
title_fullStr Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020
title_full_unstemmed Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020
title_short Characterization of Swine Influenza A(H1N2) Variant, Alberta, Canada, 2020
title_sort characterization of swine influenza a(h1n2) variant, alberta, canada, 2020
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632177/
https://www.ncbi.nlm.nih.gov/pubmed/34808085
http://dx.doi.org/10.3201/eid2712.210298
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