Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy

The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficac...

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Detalles Bibliográficos
Autores principales: Baj, Andreina, Novazzi, Federica, Pasciuta, Renee, Genoni, Angelo, Ferrante, Francesca Drago, Valli, Marilena, Partenope, Michele, Tripiciano, Rosalia, Ciserchia, Andrea, Catanoso, Giuseppe, Focosi, Daniele, Maggi, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632179/
https://www.ncbi.nlm.nih.gov/pubmed/34499599
http://dx.doi.org/10.3201/eid2712.211792
Descripción
Sumario:The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.

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