Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy

The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficac...

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Autores principales: Baj, Andreina, Novazzi, Federica, Pasciuta, Renee, Genoni, Angelo, Ferrante, Francesca Drago, Valli, Marilena, Partenope, Michele, Tripiciano, Rosalia, Ciserchia, Andrea, Catanoso, Giuseppe, Focosi, Daniele, Maggi, Fabrizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2021
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632179/
https://www.ncbi.nlm.nih.gov/pubmed/34499599
http://dx.doi.org/10.3201/eid2712.211792
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author Baj, Andreina
Novazzi, Federica
Pasciuta, Renee
Genoni, Angelo
Ferrante, Francesca Drago
Valli, Marilena
Partenope, Michele
Tripiciano, Rosalia
Ciserchia, Andrea
Catanoso, Giuseppe
Focosi, Daniele
Maggi, Fabrizio
author_facet Baj, Andreina
Novazzi, Federica
Pasciuta, Renee
Genoni, Angelo
Ferrante, Francesca Drago
Valli, Marilena
Partenope, Michele
Tripiciano, Rosalia
Ciserchia, Andrea
Catanoso, Giuseppe
Focosi, Daniele
Maggi, Fabrizio
author_sort Baj, Andreina
collection PubMed
description The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent.
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spelling pubmed-86321792021-12-01 Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy Baj, Andreina Novazzi, Federica Pasciuta, Renee Genoni, Angelo Ferrante, Francesca Drago Valli, Marilena Partenope, Michele Tripiciano, Rosalia Ciserchia, Andrea Catanoso, Giuseppe Focosi, Daniele Maggi, Fabrizio Emerg Infect Dis Research Letter The Delta variant of concern of severe acute respiratory syndrome coronavirus 2 is dominant worldwide. We report a case cluster caused by Delta sublineage B.1.617.2 harboring the mutation E484K in Italy during July 11–July 29, 2021. This mutation appears to affect immune response and vaccine efficacy; monitoring its appearance is urgent. Centers for Disease Control and Prevention 2021-12 /pmc/articles/PMC8632179/ /pubmed/34499599 http://dx.doi.org/10.3201/eid2712.211792 Text en https://creativecommons.org/licenses/by/4.0/Emerging Infectious Diseases is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Baj, Andreina
Novazzi, Federica
Pasciuta, Renee
Genoni, Angelo
Ferrante, Francesca Drago
Valli, Marilena
Partenope, Michele
Tripiciano, Rosalia
Ciserchia, Andrea
Catanoso, Giuseppe
Focosi, Daniele
Maggi, Fabrizio
Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_full Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_fullStr Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_full_unstemmed Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_short Breakthrough Infections of E484K-Harboring SARS-CoV-2 Delta Variant, Lombardy, Italy
title_sort breakthrough infections of e484k-harboring sars-cov-2 delta variant, lombardy, italy
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632179/
https://www.ncbi.nlm.nih.gov/pubmed/34499599
http://dx.doi.org/10.3201/eid2712.211792
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