Rapid Assessment of Binding Affinity of SARS-COV-2 Spike Protein to the Human Angiotensin-Converting Enzyme 2 Receptor and to Neutralizing Biomolecules Based on Computer Simulations

SARS-CoV-2 infects humans and causes Coronavirus disease 2019 (COVID-19). The S1 domain of the spike glycoprotein of SARS-CoV-2 binds to human angiotensin-converting enzyme 2 (hACE2) via its receptor-binding domain, while the S2 domain facilitates fusion between the virus and the host cell membrane...

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Detalles Bibliográficos
Autores principales: Buratto, Damiano, Saxena, Abhishek, Ji, Qun, Yang, Guang, Pantano, Sergio, Zonta, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8632240/
https://www.ncbi.nlm.nih.gov/pubmed/34858396
http://dx.doi.org/10.3389/fimmu.2021.730099

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